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EC number: 601-419-7 | CAS number: 1162-60-3
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28 December 2017 - 11 January 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Version / remarks:
- 1996
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- effusion method: isothermal thermogravimetry
Test material
- Reference substance name:
- 19-norpregn-4-en-20-yn-3-one, 17-hydroxy-7-methyl, (7alpha, 17alpha-)
- EC Number:
- 601-419-7
- Cas Number:
- 1162-60-3
- Molecular formula:
- C21H28O2
- IUPAC Name:
- 19-norpregn-4-en-20-yn-3-one, 17-hydroxy-7-methyl, (7alpha, 17alpha-)
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Physical appearance: off-white to beige powder
- Test item storage: at room temperature
Constituent 1
- Specific details on test material used for the study:
- Decomposition temp.: > 225°C
Results and discussion
Vapour pressureopen allclose all
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: mean of 2 measurements
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: mean of 2 measurements
Any other information on results incl. tables
Results of the Vapour pressure Isothermal TGA Analysis
Temperature |
Weight loss |
νT |
log νT |
log PT |
PT |
140 |
0.689087 |
8.23x10-5 |
-4.08 |
-0.09 |
0.81 |
|
0.673180 |
8.04x10-5 |
-4.09 |
-0.10 |
0.79 |
150 |
1.21848 |
1.45x10-4 |
-3.84 |
0.23 |
1.7 |
|
1.16188 |
1.39x10-4 |
-3.86 |
0.20 |
1.6 |
160 |
2.63321 |
3.14x10-4 |
-3.50 |
0.65 |
4.5 |
|
2.43577 |
2.91x10-4 |
-3.54 |
0.61 |
4.1 |
170 |
5.62734 |
6.72x10-4 |
-3.17 |
1.08 |
12 |
|
5.56993 |
6.65x10-4 |
-3.18 |
1.07 |
12 |
Vapour Pressure of the Test Item
Temperature |
log PT |
PT |
PT |
20 |
-7.26 |
5.4x10-8 |
4.1x10-10 |
25 |
-6.85 |
1.4x10-7 |
1.1x10-9 |
Applicant's summary and conclusion
- Conclusions:
- The vapour pressure of the substance at 20°C and 25°C was determined to be 5.4E-8 Pa and 1.4E-7 Pa, resp.
- Executive summary:
The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.
A vapour pressure curve was constructed from 5 reference substances. The vapour pressure of the substance at 20°C and 25°C was concluded to be 5.4E-8 Pa and 1.4E-7 Pa, resp.
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