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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
activated sludge respiration inhibition testing
Study period:
1997
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Justification for type of information:
OECD 301F Ready Biodegradability study (Givaudan Study No. 97-E78) two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.

The curves obtained with the Reference Substance alone and with the JAVANOL + Reference Substance demonstrate no toxic effect of JAVANOL on the micro-organisms at the 100 mg/L test concentration.
Key result
Duration:
38 d
Dose descriptor:
EC0
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other:
Remarks:
OECD 301F Ready Biodegradability study (Givaudan Study No. 97-E78) two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.
Validity criteria fulfilled:
yes
Conclusions:
OECD 301F Ready Biodegradability study (Givaudan Study No. 97-E78) two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.

The curves obtained with the Reference Substance alone and with the JAVANOL + Reference Substance demonstrate no toxic effect of JAVANOL on the micro-organisms at the 100 mg/L test concentration.

The EC0 is, therefore, considered to be 100 mg/L for JAVANOL.

Description of key information

In an OECD 301F Ready Biodegradability study two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.


The curves obtained with the Reference Substance alone and with the JAVANOL + Reference Substance demonstrate no toxic effect of JAVANOL on the micro-organisms at the 100 mg/L test concentration.


The EC0 is, therefore, considered to be 100 mg/L for JAVANOL.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
100 mg/L

Additional information

In an OECD 301F Ready Biodegradability study two toxicity control incubates were exposed during the 38-day incubation containing 100 mg/L of JAVANOL + 100 mg/L of the Reference Substance (Sodium Benzoate) + 30 mg/L of Inoculum.


The curves obtained with the Reference Substance alone and with the JAVANOL + Reference Substance demonstrate no toxic effect of JAVANOL on the micro-organisms at the 100 mg/L test concentration.


The EC0 is, therefore, considered to be 100 mg/L for JAVANOL.