Ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate

Endpoint summary

Description of key information

Summary Table

	Key value	Comments
Adsorption / desorption	Arithmetic mean KOC at 20 ˚C: 2440 L/kg (n = 9)	EPA 163-1
Henry’s law constant	3.3E-05 Pa m3/mol at 25 ˚C	Calculation

Additional information

Volatilisation study (Reischmann 1994)

A mixture of [phenoxyphenoxy-U-14C]-labelled test substance and unlabelled test substance was sprayed onto the surface of Speyer 2.1 soil (sand, 0.5% OC, pH 4.8) for studying the volatilisation of the substance. The study was performed by following BBA IV 6-1 guideline and was in compliance with GLP criteria. The treated area was 20.5 cm2 and the dose was equivalent to 146 (0.003 m/s experiment) and 181 g/ha (1 m/s experiment). The moisture content of the soil was brought at 60% of the MWHC. The treated soil was placed in a closed chamber. An air stream (0.003 or 1 m/s) was passed through the chamber (276 mL/min equivalent to 60 air exchanges per hour and 2040 mL/min equivalent to 20571 air exchanges per hour, respectively) for a period of 24 hours. Outgoing air of the 0.003 m/s was passed through two 2-methoxyethanol traps. The temperature was 20 ± 2°C and relative humidity was 35%. Traps and soil of the 0.003 m/s experiment were sampled after 0 (soil), 1, 3, 6 and 24 hours. For the 1 m/s experiment, soil was sampled after 24 hours. Radioactivity in the traps was determined by LSC.

The majority of radioactivity was recovered from the soil (≥ 89% AR). Trapped volatilised radioactivity was ≤ 0.04% AR. The results showed that 3.1% and 6.9% of applied radioactivity volatilised from the soil surface after 24 hours exposure to air at 0.003 and 1 m/s, respectively.

Volatilisation study (Sandmeier 1993)

The volatilisation of the test substance was investigated in a BBA IV 6-1 guideline followed study. The study was in compliance with GLP criteria as well. A mixture of [phenoxyphenoxy-U-14C]-labelled test substance and unlabelled test substance in blank formulation was sprayed onto the surface of bush bean plants grown in 12 cm pots and thinned to 6 leaves/plant. The spray area was 7488 cm2 and the dose was equivalent to 536 g test substance/ha. The treated bush bean plants were placed in a closed chamber. An air stream (1 m/s) was passed through the chamber for a period of 24 hours. A day/night cycle of 14 hours light/10 hours dark was applied. The temperature was between 20 and 21 °C and relative humidity was 35 - 40%. The leaves of two plants were sampled immediately after application and after 1, 3, 6 and 24 hours. Combustion/LSC and TLC were used to analyse the radioactivity in the samples.

After 24 hours, 97.9% of the radioactivity present on the bean leaves immediately after application was recovered from the leaves, indicating insignificant volatilisation of the test substance from leaf surfaces (2.1%). At intermediate time points, maximum 6.0% of the initial residue was lost. The majority of radioactivity was recovered in the washings (95 - 100%) and was essentially the test substance (> 98%).