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Diss Factsheets
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EC number: 242-177-9 | CAS number: 18297-63-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The registered (parent) substance 1,3-bis(trimethylsilyl)urea hydrolyses rapidly under environmentally relevant conditions (DT50 < 10 min at pH 4, 7 and 9, 20 °C, OECD 111) and forms the silanol hydrolysis product trimethylsilanol (CAS No. 1066-40-6) and urea (CAS No. 57-13-6), which are considered the relevant assessment entities for the environmental hazard and risk assessment according to Guidance R.16 (ECHA, 2016).
Trimethylsilanol
The silanol hydrolysis product trimethylsilanol (TMS) is considered to be a stable degradant of the registered (parent) substance. It is characterized by a high, estimated water solubility of 1000 g/L (QSAR) and an estimated vapour pressure of 1850 Pa (QSAR). It is not readily biodegradable but has a low, estimated log Kow of 1.14 (QSAR), and a low estimated log Koc in the range of 0.99 to 1.64 (QSAR), indicating a low potential for bioaccumulation and adsorption to soil and sediment. Based on its properties, trimethylsilanol is expected to predominantly partition to the water column. The SimpleTreat model v4.0 predicts 99.07% of the substance to partition to water and the remaining fraction to air (0.33%), the primary settler (0.39%) and surplus sludge (0.21%).
Urea
Urea is well described in the public domain. It is expected to primarily distribute into the water (99.84%) and air (0.16%) compartments, based on modeling results (Mackay level 1). However, according to worldwide use patterns, the highest environmental exposure is to soil because of its wide use as fertilizer. Environmental exposure by consumer use is considered insignificant (OECD SIDS, 2002).
Reference
OECD SIDS (2002); Urea, CAS 57-13-6, SIAM 2 Final Assessment Report, UNEP Publications
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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