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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20 March 2017 to 01 August 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- <= 0.001 g/L
- Conc. based on:
- test mat.
- Remarks:
- calcium content
- Loading of aqueous phase:
- 0.1 g/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- >= 8.6 - <= 8.7
- Key result
- Water solubility:
- <= 0 g/L
- Conc. based on:
- test mat.
- Remarks:
- boron content
- Loading of aqueous phase:
- 0.1 g/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- >= 8.6 - <= 8.7
- Key result
- Water solubility:
- < 0.001 g/L
- Conc. based on:
- test mat.
- Remarks:
- Total Organic Carbon
- Loading of aqueous phase:
- 0.1 g/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- >= 8.6 - <= 8.7
- Conclusions:
- The water solubility of the test item was determined to be ≤ 7.8 x 10E-04 gCa/L, ≤ 3.2 x 10E-04 gB/L and < 1 x 10E-03 gTOC/L at 20.0 ± 0.5 °C from a nominal loading rate of 0.1 g/L.
- Executive summary:
GUIDELINE
The determination was carried by the flask method using a procedure designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
RESULTS
The water solubility of the test item was determined to be ≤ 7.8 x 10E-04 gCa/L, ≤ 3.2 x 10E-04 gB/L and < 1 x 10E-03 gTOC/L at 20.0 ± 0.5 °C from a nominal loading rate of 0.1 g/L.
Reference
PRELIMINARY TEST
- The estimates of water solubility at 20.0 ± 0.5°C are shown in Table 9 (below).
DEFINITIVE TEST
-The counts per second relating to the standard and sample solutions are shown in Table 10 (attached) for calcium and Table 11 (attached) for boron.
- The calibration curves from which the sample calcium concentrations were interpolated are presented in Figure 3 and Figure 4 (attached).
- The calibration curve from which the sample boron concentrations were interpolated is presented in Figure 5.
- The total organic carbon concentration relating to the standard and sample solutions are shown in Table 12 (attached).
- The concentration (g/L) of test item in the sample solutions is shown in Table 13 (below).
TABLE 9 – PRELIMINARY ESTIMATES OF WATER SOLUBILITY
Loading rate (g/L) |
Concentration calcium (g/L) |
Concentration boron (g/L) |
TOC (g/L) |
pH |
0.1 |
< 1 x 10-4 |
< 1 x 10-4 |
≤1.2 x 10-3 |
6.4 |
1 |
2.0 x 10-3 |
8.6 x 10-4 |
4.8 x 10-3 |
7.2 |
TABLE 13 – CONCENTRATION OF TEST ITEM IN SAMPLE SOLUTIONS
Sample number |
Calcium concentration – original (g/L) |
Calcium concentration – repeat (g/L) |
Boron concentration (g/L) |
TOC |
Solution pH |
1 |
< 1 x 10-4 |
1.3 x 10-4 |
< 1 x 10-4 |
< 1 x 10-3 |
8.7 |
2 |
< 1 x 10-4 |
2.1 x 10-4 |
1.2 x 10-4 |
< 1 x 10-3 |
8.7 |
3 |
7.0 x 10-4 |
7.8 x 10-4 |
3.2 x 10-4 |
< 1 x 10-3 |
8.6 |
Overall calcium result: ≤7.8 x 10E-04 gCa/L at 20.0 ± 0.5°C
Overall boron result: ≤3.2 x 10E-04 gB/L at 20.0 ± 0.5°C
Overall TOC result: < 1 x10E-03 gTOC/L at 20.0 ± 0.5°C
Description of key information
The water solubility of the test item was determined to be ≤ 7.8 x 10E-04 gCa/L, ≤ 3.2 x 10E-04 gB/L and < 1 x 10E-03 gTOC/L at 20.0 ± 0.5 °C from a nominal loading rate of 0.1 g/L (OECD 105 and EU Method A.6).
Key value for chemical safety assessment
- Water solubility:
- 0 g/L
- at the temperature of:
- 20 °C
Additional information
GUIDELINE
The determination was carried by the flask method using a procedure designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
RESULTS
The water solubility of the test item was determined to be ≤ 7.8 x 10E-04 gCa/L, ≤ 3.2 x 10E-04 gB/L and < 1 x 10E-03 gTOC/L at 20.0 ± 0.5 °C from a nominal loading rate of 0.1 g/L.
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