Registration Dossier
Registration Dossier
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EC number: 242-665-1 | CAS number: 18912-80-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
There is no experimental data available for the substance. However, there are two studies available for the closely related substance 2 -(2 -butoxyethoxy)ethanol (DEGBE). One is a GLP guideline limit study which showed no adverse effects at 100mg/L to D suspicatus after 96hrs. The other is a published study which measured an EC50 (72hr) of 1100mg/L to P. subcapitata. A reliable QSAR predicts that DEGBE and DEGiBE (2 -(2 -isobutoxyethoxy)ethanol) will have very similar toxicity, with, if anything DEGBE being slightly more toxic. The prediction for DEGBE of a 96hr of 860mg/L is remarkably close to the QSAR estimate. This all supports the case that the data from DEGBE can be extrapolated to DEGiBE in a conservative manner. The data from DEGBE is sufficient to fulfill the data requirements for this end point and to conclude that DEGiBE does not need to be classified as dangerous to the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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