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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Physical state/appearance,colour:
Appearance, physical state and colour were tested as part of the analytical characterization of the test item. The test item is a non-volatile, odourless, colourless solid.
Melting point:
The study was conducted in accordance with OECD test guidelines n. 102 and EU method A.1, using the capillary method.. The melting range of LZ 61000 was found to be 128.5°C ± 0.14°C (95% confidence interval).
Boiling point:
The study was conducted in accordance with OECD test guidelines n. 103 and EU method A.2, using the Siwoloboff method. Boiling point of the test item was not observed before the apparent degradation of the test item above 200°C.
Relative density:
The study was conducted according to OECD test guideline no. 109 and EU method A.3, using a gas comparison pycnometer. The relative density was determined to be 1.70.
Particle size distribution:
The particle size distribution of the test item was determined by means of Laser Diffraction Analysis (ISO 13320)using the medium volume (wet) module (MVM).The D50 of the test item was determined to be 15.7 µm, the D10 was 7.67 µm and the D90 was 45.6 µm. The MMAD of the test item, for the relative density and the mean D50, was calculated to be 20.5 µm.
Vapor pressure:
The study was conducted according to OECD test guideline no. 104 and EU method A.4, applying the isothermal TGA effusion method. No decomposition of the test tem observed. The vapor pressure was found to be 3.6 x 10E-2 Pa = 2.7 x 10E-4 mm Hg at 20°C and 6.3 x 10E-2 Pa = 6.3 x 10E-4 mm Hg at 25°C.
Partition coefficient:
The partition coefficient n-octanol/water (Pow) was measured according to OECD test method no. 117, using the HPLC-method with UV-detection. The substance to be registered is not stable and hydrolyses within a few minutes when in contact with water: Therefore, it was decided to measure the partition coefficient of the degradation product itself. The Log Pow (n-octanol/water) of the degradation product was determined to be 0.885 at 25 °C.
Water solubility:
The water solubility was measured according to OECD test method no. 105, using the flask shake method with HPC/UV-detection. The substance to be registered is not stable and hydrolyses within a few minutes when in contact with water: Therefore, it was decided to measure the water solubility of the degradation product itself. The water solubility of LZ 399 was found to be 276 ± 16 g/L at 20°C..
Surface tension of an aqueous solution:
The study was conducted in accordance with OECD test guidelines no. 115 and EU method A.5, using the ring method. The surface tension value was found to be 68.72 mN/m at 20.17°C. As the surface tension value of the 90% of the saturated aqueous solution of the test was greater than 60 mN/m, the test item is classified as not being a surface active substance.
Flash point:
The study does not need to be conducted because the flash point is only relevant to liquids and low melting point solids.
Flammability:
The study was performed in accordance with EU method A.10. In the pre-test, a hot flame from a gas burner was applied to one end of the powder train for a maximum of 2 minutes. The test item did not propagate by combustion neither by burning with a flame or smouldering, therefore, no further testing was performed. The test item, LZ 61000 is considered to be non-flammable under the conditions of this test.
The studies A.12 and A.13 were not performed, as the substance will hydrolyze immediately in contact with water or humid air. There are no flammable gases formed during hydrolysis. Hydrolysis was confirmed in a hydrolysis study according to OECD 111.
Autoflammability:
The study was performed in accordance with EU method A.16. No ignition of the test item was observed up to 400°C, but the test item was melted. Based on the results, the test item is considered not to be auto-flammable.
Explosiveness:
Study scientifically not necessary; study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidizing properties:
Study scientifically not necessary; study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and the substance is incapable of reacting exothermically with combustible materials.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.