Registration Dossier
Registration Dossier
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EC number: 421-450-8 | CAS number: 154702-15-5
Endpoint summary
Administrative data
Description of key information
This study was conducted by a limit test. A total of 15 female SD rats and 15 male SD rats were used in the limit test and were randomized into three groups, specifically, control group, treatment group and satellite group, 5 males and 5 females in each group. Each rat in treatment group and satellite group was continuously repeatedly dosed at 1000mg/kg body weight for 6 h (+10min) per day for a total of 28 days dose period. Cage-side observation was performed once daily after rats were transferred. Cage-side observation was performed from D- 1 to D27 in control group, satellite group and treatment group, while kept for a further 14 days for satellite group without dose administration to detect whether recovery from or persistence of toxic effects in 2 weeks.
Based on the results of the study, percutaneous repeated dose of 1000 mg/kg Diethylhexyl Butamido Triazone for 28 days did not cause mortality and toxic effects and no test item related functional and organic damages of visceral lesions were observed.
Key value for chemical safety assessment
- Toxic effect type:
- dose-dependent
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
- Study duration:
- subchronic
- Species:
- rat
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Based on the study available, the substance is not classified for the specific target organ toxicity.
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