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EC number: 617-298-9 | CAS number: 82097-50-5
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
Two phytotoxicity studies with a formulation containing the substance and two other studies with metabolites tested in parallel to the mother compound are available and briefly discussed here.
Key value for chemical safety assessment
Additional information
Two studies on phytoxicity were conducted with a formulation containing the substance. These studies are not summarized as an endpoint study entry but are briefly discussed here.
In a non-target terrestrial plant seedling emergence and seedling growth test, according to OECD Guideline 208 (2006) and under GLP, planted seeds of three monocot species and seven dicot species were sprayed with a series of seven test concentrations of formulation. Nominal test concentrations used in the definitive test for all test species ranged from 0.05 to 37.5 g formulation/ha, corresponding to 0.05 to 37.5 mg substance/L solution. At 7, 14 and 21 days after 50% emergence in controls assessments were made of the emergence, mortality and visual phytotoxicity expressed as a percentage of healthy untreated control plants. The resulted ER50 values were ranging from 1.78 to >37.5 g formulation/ha, corresponding to 1.78 to >37.5 mg substance/L solution. Allium cepa (onion) was the most sensitive species, with an ER50 of 1.51 g formulation /ha, corresponding to 1.51 mg substance/L solution based on biomass (Bramby-Gunary J 2011a).
In a non-target terrestrial plant vegetative vigour test according to OECD Guideline 227 (2006), but not conducted under GLP, young plants of three monocot species and seven dicot species were sprayed with a series of seven test concentrations of formulation. Nominal test concentrations used for all test species ranged from 0.05 to 37.5 g formulation/ha, corresponding to 0.05 to 37.5 mg substance/L solution. At 7, 14 and 21 days after application assessments were made of the mortality and visual phytotoxicity expressed as a percentage of healthy untreated control plants. The growth of test plants was evaluated at test termination (21 days after application) by assessing height and dry weight (biomass). The resulted ER50 values ranging from 1.08 to >37.5 g/ha, corresponding to 1.08 to >37.5 mg substance/L solution. Brassica napus (Oilseed rape) was the most sensitive species, with an ER50 of 1.08 g formulation/ha, corresponding to 1.08 mg substance/L solution based on biomass (Bramby-Gunary J., 2011b).
Two studies on phytoxicity of major metabolites in parallel to the substance not conducted under GLP were also available and summarized as below.
One study was conducted for effects of the substance and 4 metabolites on seedling emergence and vegetative vigour. These were studied on six plant species at application rates of 4, 8, 16 and 32 g test item/ha, corresponding to 20, 40, 80 and 160 mg substance/kg solution. Phytotoxic effects such as stunting, leaf distortion and chlorosis effects on some species resulted from the application rates of 4 g substance/ha, corresponding to 20 mg test item/kg solution. The metabolites produced no phytotoxic effects on any of the plant species tested (Stefanut 2012).
The other study was conducted separately on one metabolite and the mother compound by applying pre-emergence and post-emergence to a range of monocotyledon and dicotyledon terrestrial non-target plant species at application rates of 2, 4, 8 and 16 g test item/ha, corresponding to 10, 20, 40 and 80 mg test item/kg solution. The mother compound showed phytotoxic effects such as stunting, chlorosis, death from 2 g test item/ha to 16 g test item/ha, corresponding to 10 - 80 mg test item/kg solution for both seedling emergence and vegetative vigour. The metabolite showed no phytotoxic effects for seedling emergence and showed phytotoxic effects on Sinapis arvensis such as stunting, darker leaves and leaf distortion at 2 g test item/ha, corresponding to 10 mg test item/kg solution, elongated distorted leaves and stunting from 4 g test item/ha to 16 g test item/ha, corresponding to 10 to 40 mg test item/kg solution and elongated stems at 8 g test item/ha, corresponding to 80 mg test item/kg solution for vegetative vigour (Tomoroga 2011).
Group | Species | Duration | Most sensitive endpoint | Effects | Author/Year | |
Seedling emergence – formulation (containing 20% substance): single pre-emergence application at 0.05, 0.15, 0.46, 1.4, 4.2, 12.5 and 37.5 g formulation/ha corresponding to 0.05, 0.15, 0.46, 1.4, 4.2, 12.5 and 37.5 mg substance/kg solution | ||||||
Monocotyledoneae | Triticum aestivum, wheat | 21 d | All | ER50 > 37.5 | Bramby-Gunary / 2011a | |
Dicotyledoneae | Glycine max, soybean | 21 d | Height | ER50 = 27.58 |
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Vegetative vigour - formulation (containing 20% substance): single post-emergence application at 0.05, 0.15, 0.46, 1.4, 4.2, 12.5 and 37.5 g formulation/ha corresponding to 0.05, 0.15, 0.46, 1.4, 4.2, 12.5 and 37.5 mg substance/kg solution | ||||||
Monocotyledoneae | Triticum aestivum, wheat | 21 d | All | ER50 > 37.5 | Bramby-Gunary / 2011b | |
Dicotyledoneae | Glycine max, soybean | 21 d | Height | ER50 = 23.68 |
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three metabolites (in parallel to substance): Seedling emergence and Vegetative Vigour: single pre- respectively post-emergence application at 4, 8, 16 and 32 g/ha, corresponding to 20, 40, 80 and 160 mg substance/kg solution | ||||||
No phytotoxicity was found from the metabolites either pre- or post-emergence on 6 plant species (oilseed rape, sugar beet, ryegrass, White mustard Sinapis alba, chickweed Stellaria media, Carelessweed Amaranthus retroflexus) targeted in a herbicidal activity screen while triasulfuron exhibited significant phytotoxicity in all species at any rate. | Stefanut / 2012 | |||||
one metabolite (in parallel to substance): Seedling emergence and Vegetative Vigour: single pre- respectively post-emergence application at 2, 4, 8 and 16 g/ha, corresponding to 10, 20, 40 and 80 mg substance/kg solution | ||||||
No phytotoxicity activity was found from the metabolites either pre- or post-emergence on 6 plant species (oilseed rape, sugar beet, ryegrass, Wild mustard Sinapis arvensis, chickweed Stellaria media, Carelessweed Amaranthus retroflexus) apart from moderate phytotoxicity in S. arvensis at all rates following post emergence treatment, while triasulfuron exhibited significant phytotoxicity in all species in both tests at any rate. | Tomoroga / 2011 | |||||
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