Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 240-178-9 | CAS number: 16039-53-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study not according to standard protocol but good quality and considered useful for assessing food chain transfer of zinc. Culture medium, test water conditions well described and relevant.
Data source
Reference
- Reference Type:
- publication
- Title:
- Food chain analysis of exposures and risks to wildlife at a metal contaminated wetland
- Author:
- Pascoe GA, Blanchet RJ and Linder G
- Year:
- 1 996
- Bibliographic source:
- Arch. Environ. Contam. and Toxicol. 30,306-318
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- food chain analysis in a contaminated natural environment
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Zinc
- EC Number:
- 231-175-3
- EC Name:
- Zinc
- Cas Number:
- 7440-66-6
- IUPAC Name:
- zinc
- Details on test material:
- data referred to as "zinc" in general, no speciation given.
Constituent 1
Sampling and analysis
- Details on sampling:
- Sample collection for the food chain analysis was performed over different field seasons at a 450 acre portion of wetland, located in the Milltown reservoir sediment superfund site , Montana, (Rocky Mountains), USA. sampling was done according to USEPA and ASTM guidelines.
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- other: various wildlife species
- Details on test organisms:
- Various species of aquatic and terrestrial invertebrates, minnows, fish, small mammals and vegetation were included in the analysis.
Study design
- Route of exposure:
- other: feed and aqueous
- Test type:
- field study
- Water / sediment media type:
- natural sediment: freshwater
Test conditions
- Test temperature:
- ambient
- Details on test conditions:
- ambient conditions (field study)
- Nominal and measured concentrations:
- concentrations in control environment were (in mg Zn/kg): sediment: 52, soil: 49
concentrations in contaminated environment were (in mg Zn/kg): sediment: 1426, soil:1950
concentration in water was (µg Zn/l) 5 (control) and 149 (contaminated) - Reference substance (positive control):
- no
Results and discussion
Bioaccumulation factoropen allclose all
- Type:
- BAF
- Value:
- 4 060
- Basis:
- whole body d.w.
- Calculation basis:
- steady state
- Remarks on result:
- other: aquatic invertebrates: control water
- Remarks:
- Conc.in environment / dose:5
- Type:
- BAF
- Value:
- 3 483
- Basis:
- whole body w.w.
- Calculation basis:
- steady state
- Remarks on result:
- other: aquatic invertebrates, contaminated water
- Remarks:
- Conc.in environment / dose:149
- Type:
- BAF
- Value:
- 2 600
- Basis:
- whole body d.w.
- Calculation basis:
- steady state
- Remarks on result:
- other: snails, control water
- Remarks:
- Conc.in environment / dose:5
- Type:
- BAF
- Value:
- 779
- Basis:
- whole body d.w.
- Calculation basis:
- steady state
- Remarks on result:
- other: snails, contaminated water
- Remarks:
- Conc.in environment / dose:149
- Type:
- BAF
- Value:
- 177
- Basis:
- whole body w.w.
- Calculation basis:
- steady state
- Remarks on result:
- other: fish, contaminated water
- Remarks:
- Conc.in environment / dose:149
- Details on results:
- concentrations in biota were considered steady state (field study). BAF are compared between control conditions and contaminated conditions.
- Reported statistics:
- all values were reported with standard deviations
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Field study of good quality and considered useful for assessing the effect on the endpoint
- Executive summary:
Food chain transfer was studies in several species of wildlife, and results observed between a control area and a contaminated area were compared. In all biota studies, being aquatic or terrestrial, BAFs were lower in biota exposed to elevated zinc, as compared to the controls.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.