Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-204-7 | CAS number: 1313-27-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_toxicological-information.png)
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The substance is not considered to have sensitising properties, based on reliable in vivo skin sensitisation studies in guinea pigs with the substance and/or with suitable surrogate substances (read-across): the moderately to very soluble molybdenum substance sodium molybdate, ammonium dimolybdate, molybdenum trioxide and roasted molybdenite concentrate did not show any sensitising effects in reliable guinea pig maximisation studies. The inert substance MoS2 also was not sensitising.
To avoid unnecessary (animal) testing, a comprehensive grouping and read-across concept has been developed amongst several molybdenum containing substances. This grouping/category approach is described in detail in a separate report, in accordance with the ECHA's "Read-Across Assessment Framework" (RAAF). This document is attached to section 13 in the technical dosser and to the CSR.
The main conclusion is that read-across/grouping of molybdenum substances is justified for systemic effects, including sensitisation, based on the formation of the molybdate ion from all substances in the category, as the driver for any toxicity. The non-molybdenum moieties in the substances, such as iron, ammonium, calcium or sodium do not contribute to toxicity, or at least to a lesser extent than the molybdenum moiety. The substances for which skin sensitisation studies are available are moderately to very soluble and represent worst-case surrogates for less soluble molybdenum substances. For details, see “read-across document” in IUCLID section 13.
In conclusion, the registered substance is not considered to have sensitising properties, and no hazard classification is required for sensitisation.
Justification for classification or non-classification
The substance is not considered to have sensitising properties, based on reliable in vivo skin sensitisation studies in guinea pigs with the substance and/or with suitable surrogate substances (read-across): the moderately to very soluble molybdenum substance sodium molybdate, ammonium dimolybdate, molybdenum trioxide and roasted molybdenite concentrate did not show any sensitising effects in reliable guinea pig maximisation studies. The inert substance MoS2 also was not sensitising.
To avoid unnecessary (animal) testing, a comprehensive grouping and read-across concept has been developed amongst several molybdenum containing substances. This grouping/category approach is described in detail in a separate report, in accordance with the ECHA's "Read-Across Assessment Framework" (RAAF). This document is attached to section 13 in the technical dosser and to the CSR.
The main conclusion is that read-across/grouping of molybdenum substances is justified for systemic effects, including sensitisation, based on the formation of the molybdate ion from all substances in the category, as the driver for any toxicity. The non-molybdenum moieties in the substances, such as iron, ammonium, calcium or sodium do not contribute to toxicity, or at least to a lesser extent than the molybdenum moiety. The substances for which skin sensitisation studies are available are moderately to very soluble and represent worst-case surrogates for less soluble molybdenum substances. For details, see “read-across document” in IUCLID section 13.
In conclusion, the registered substance is not considered to have sensitising properties, and no hazard classification is required for sensitisation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)