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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 228-250-8 | CAS number: 6197-30-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Octocrilene is not bioaccumulative and not very bioaccumulative according to the REACH PBT/vPvB criteria.
Key value for chemical safety assessment
- BCF (aquatic species):
- 859 dimensionless
- BMF in fish (dimensionless):
- 0.034
Additional information
The bioaccumulation of octocrilene in zebra fishDanio reriowas investigated using a flow through system set up according to OECD 305. The fish were exposed via the water to the 14C-radio labeled test substance for 28 days. After a depuration period of 15 days the test was terminated and a mean growth and lipid corrected BCF of 858 at a concentration of 0.1 and 1.0 µg/l, respectively based on the whole body wet weight was determined (BASF AG, 2008). This BCF takes into account both parent and any possible metabolite (i.e. transformation products such as glucuronides and sulfates), and thus may be considered as a worst case.
Furthermore, a second fish bioaccumulation study using rainbow troutOncorhynchus mykissand dietary exposure was carried out with 14C radiolabeled test substance (1 µg//g feed) for 14 days (BASF SE,
DSM Nutritional Products AG, Merck KGaA, Symrise AG, 2018). The resulting lipid and growth corrected kinetic BMF was 0.0335.
Available scientific literature on measured test substance concentration in various aquatic organisms was reviewed and compared to the results from the two OECD 305 studies. Overall, it was concluded that the substance is not considered as bioaccumulative and not as very bioaccumulative according to the REACH PBT/vPvB-criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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