Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 278-636-5 | CAS number: 77182-82-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The substance is stable for hydrolysis and is considered as not readily biodegradable based on OECD 301 tests. Glufosinate-ammonium is photolytically stable in sterile aqueous solutions. Direct or indirect photolytic transformation in water therefore does not significantly contribute to the elimination of glufosinate-ammonium residues from the aquatic environment. No quantum yield was determined due to a lack of absorption of light by glufosinate-ammonium in the relevant wavelength range of visible light. Photodegradation of glufosinate-ammonium was studied on the surface of a sandy loam soil. No transformation products were formed being specific for photolytic degradation. Conclusively, photolytical transformation processes on soil surfaces do not play a role for the elimination of glufosinate-ammonium residues from the soil environment.
The degradation of 14C-glufosinate-ammonium was investigated under the conditions of two water /sediment studies. The degradation under conditions of a water/sediment study was also investigated following separate dosing of metabolite AE F061517 (MPP).
Route of degradation:
Glufosinate-ammonium was degraded via a similar route as found for aerobic soil, i.e. via oxidative deamination to AE F065594 (PPO) as a minor metabolite, followed by the formal but multistep loss of methylene groups each to result in AE F061517 (MPP, maximum 79.8% at day 14) and AE F064619 (MPA, maximum 19.9% at day 50) by oxidative processes. Alternatively, the transformation of AE F061517 (MPP) resulted via dehydrogenation (formal loss of hydrogen) in the formation of 3-[hydroxy(methyl)phosphoryl]acrylic acid (P-X, AE 0015081, maximum 12.5% at day 50). Metabolite N-acetylglufosinate (NAG) was observed at a maximum of 13.7% at day 1 thus demonstrating the transient character.
Rate of degradation:
Water/sediment studies were kinetically evaluated following the FOCUS kinetics guidance. For total systems the kinetic evaluation according to FOCUS guidance (Level P-I) resulted in geometric mean degradation half-lives of 8.7 days for glufosinate-ammonium and 219.4 days for MPP (AE F061517). For MPA (AE F064619) a DegT50 of 33.3 days was derived for total systems.
According to Echa guidance R.16, equation R.16 -9, the DT50 of glufosinate-ammonium for the whole system of 8.7 days at 20°C resulted in a half-life of 16.5 days or a degradation rate of 0.042 d-1 at 12°C.
Additionally the degradation of 14C-glufosinate-ammonium was investigated in a pelagic-water study at 20 °C. The half-life was estimated to be 54.3 days. This value is considered as worst-case figure due to the lack of microbial activity based on the absence of the sediment phase.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.