Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 237-253-3 | CAS number: 13709-42-7
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no study available
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Additional information
This section will be completed upon availability of the finalised OECD 422 study report.
Short description of key information:
A screening for reproductive / developmental toxicity study (as required under section 8.7.1 of Annex VIII) has been conducted according to OECD Guideline 422. Upon review of the draft study report the validity of the study has been called into question because of the high number of non-pregnant females and total litter losses observed in the treated groups during the study period. Discussions between the laboratory which conducted the study and representatives of the registrants are ongoing. As soon as this matter is resolved a registration update will be provided to include data to address this endpoint.
Effects on developmental toxicity
Description of key information
A screening for reproductive / developmental toxicity study (as required under section 8.7.1 of Annex VIII) has been conducted according to OECD Guideline 422. Upon review of the draft study report the validity of the study has been called into question because of the high number of non-pregnant females and total litter losses observed in the treated groups during the study period. Discussions between the laboratory which conducted the study and representatives of the registrants are ongoing. As soon as this matter is resolved a registration update will be provided to include data to address this endpoint. The requirement for a pre-natal developmental toxicity study (as required under section 8.7.2. of Annex IX) will be considered once the outstanding issues concerning the OECD 422 study are resolved.
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Additional information
This section will be completed upon availability of the finalised OECD 422 study report.
Justification for classification or non-classification
Pending availability of the finalised OECD 422 study, the substance does not require classification for reproductive or developmental toxicity effects under Regulation (EC) No 1272/2008.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
