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EC number: 479-330-6 | CAS number: 67226-45-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_classification-and-labelling-and-pbt-assessment.png)
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Persistence – Conclusion
1-Butylpyridinium heptachlorodialuminate (CAS 67226-45-3) is an ionic liquid that consist of an N-butylpyridinium cation and a heptachloroaluminate anion that hydrolyses very rapidly in contact with water. According to literature systems with chloroaluminate anions must be classified as extremely hygroscopic and labile towards hydrolysis. The aluminium (III) halides are extremely sensitive to even the smallest amounts of water. In the literature it is described that when water is added to chloroaluminate ionic liquid of any composition, an exothermic reaction occurs with the evolution of HCI. This reaction produces oxide- and proton-containing species, both of which can interact with other solutes.
Therefore, the substance itself is not persistent.
The hydrolysis product N-Butylpyridinium chloride (CAS 1124-64-7) is not readily biodegradable according to OECD criteria (see Section 4). Therefore, this hydrolysis product may persist in the environment (P).
Bioaccumulation– Conclusion
The hydrolysis product N-Butylpyridinium chloride (CAS 1124-64-7) has low log Kow values (<3) and, therefore, is not likely to bioaccumulate.
Furthermore, Assessment of the toxicokinetic behaviour of the substance and the breakdown products formed after hydrolysis in aqueous environment showed that all these compounds are relatively poorly absorbed, and fairly rapidly eliminated by the body and therefore no potential for accumulation is foreseen.
Therefore, the substance and hydrolysis products do not meet the screening criterion for bioaccumulation and are not considered to be bioaccumulative (B) or very bioaccumulative (vB).
Toxicity – Conclusion
The substance does not meet the classification for toxic (T) in the environment because the short term data available with aquatic invertebrates and algae present EC values >1 mg/L. Thus, the criteria set out in Annex XIII of Regulation (EC) No. 1907/2006 are not met and the test substance is not considered to meet the T criterion.
The substance is not classified as carcinogenic (cat. 1 or 2), mutagenic (cat. 1 or 2), or toxic for reproduction (cat. 1, 2 or 3) according to Directive 67/548/EEC or carcinogenic (cat. 1A or 1B), germ cell mutagenic (cat. 1A or 1B), or toxic for reproduction (cat. 1A, 1B or 2) according
to Regulation (EC) No. 1272/2008. There is no other evidence of chronic toxicity, as identified by the classifications T, R48 or Xn, R48 according to Directive 67/548/EEC or specific target organ toxicity after repeated exposure (STOT RE cat. 1 or 2) according to Regulation (EC) No. 1272/2008.
The test substance is not considered to meet the T criterion.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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