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Diss Factsheets
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EC number: 218-485-4 | CAS number: 2162-73-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
1) Key_Bioaccumulation: aquatic / sediment: BCFSSL= 4.5 - 6.1 L/kg for Onchorhynchus mykiss (flow-through, freshwater, OECD 305 -I: Aqueous Exposure Bioconcentration Fish Test,GLP)
2) Waiver_Bioaccumulation: aquatic / sediment: According to REACH Regulation (EC) No 1907/2006 Article 2 (9), polymers are excluded from Titles II (Registration) and VI (Evaluation).
Additional information
Bioaccumulation: aquatic / sediment
Due to the very fast hydrolysis (DT50= 37s) and the resulting instability of the test substance, it was considered most meaningful to cover the information on the bioaccumulative potential by the consideration of the degradation products. Based on the results of the hydrolysis study conducted at CURRENTA GmbH according to OECD 111, 2,4,6-triisopropyl-m-phenylene diamine (TRIDA, CAS 6318-09-08) was expected as major hydrolysis and polymeric ureas as potential minor hydrolysis product (Neuland, 2020).
Accordingly, the bioaccumulative potential was analysed for the main hydrolysis product 2,4,6-triisopropyl-m-phenylene diamine (TRIDA, CAS 6318-09-08).The study was running under GLP according to OECD TG 305-I using aqueous exosure. Based on the mean measured concentration of the test material in the test water, the bioconcentration factor was determined for steady state (BCFSS), including a normalisation to 5% lipid content (BCFSSL) and was 1.44-1.88 L/kg and 4.5-6.1 L/kg, respectively, indicating a low potential for bioaccumulation. As a worst-case assumption the upper value of 6.1 L/kg is taken as key value for further risk assessment.
Polymeric ureas are considered as polymers under REACH. Therefore they do not have to be registered and evaluated according to Chapter 1; Article 2, Paragraph 9 Regulation No. 1907/2006. Regardless of the evaluation of available data, the determination of the bioaccumulative potential of the polymeric ureas as minor hydrolysis product is waived accordingly.
Bioaccumulation: terrestrial
This is no mandatory endpoint to be fulfilled for a registration of a tonnage band of 100 - 1000 tons/year according to REACH Regulation (EC) 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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