Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Developmental toxicity / teratogenicity

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Administrative data

Endpoint:
developmental toxicity
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary source information

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Unnamed
Year:
2005
Reference Type:
secondary source
Title:
Unnamed
Year:
1998

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Developmental toxicity data from structurally related long-chain alcohols
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Alcohols, C12-13
EC Number:
278-306-0
EC Name:
Alcohols, C12-13
Cas Number:
75782-86-4
IUPAC Name:
dodecan-1-ol

Results and discussion

Results: maternal animals

Effect levels (maternal animals)

Dose descriptor:
other: weight of evidence
Basis for effect level:
other: developmental toxicity

Results (fetuses)

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
Not expected to be a developmental toxicant in the absence of maternal toxicity.