Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-179-8 | CAS number: 117-21-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Study period:
- 2004
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Remarks:
- The calculation method was validated with experimental vapor pressure data on several phthalate and chlorinated aromatic compounds, and the error of the calculation method was estimated based on these vapor pressure data.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
- Principles of method if other than guideline:
- OECD Guideline 104 supports the use of the Watson correlation for the calculation of vapor pressure. OECD does not specifically reject other calculation methods. Comparison of calculated vapor pressures of 11 compounds using the Watson correlation method and using the Advanced Chemistry Development Inc. (ACD) method showed that the ACD results were generally more accurate than the “Watson values”. This comparison was made on vapor pressure data of a wide range of chemical classes including ether, carboxylic acid, carbamate, phenol, halogenated aromatic and aliphatic, and nitro. For the estimation of the vapor pressure of 3 CLPA, a calculation approach was judged to be appropriate.
- GLP compliance:
- no
- Remarks:
- Not Applicable
- Type of method:
- other: calculation
Test material
- Reference substance name:
- 3-chlorophthalic anhydride
- EC Number:
- 204-179-8
- EC Name:
- 3-chlorophthalic anhydride
- Cas Number:
- 117-21-5
- Molecular formula:
- C8H3ClO3
- IUPAC Name:
- 4-chloro-1,3-dihydro-2-benzofuran-1,3-dione
Constituent 1
Results and discussion
Vapour pressure
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- >= 0.02 - <= 0.08 Pa
Applicant's summary and conclusion
- Conclusions:
- The vapor pressure was calculated to be 0.05 ± 0.03 Pa at 25 °C.
- Executive summary:
The vapor pressure was determined per calculation. OECD Guideline 104 supports the use of the Watson correlation for the calculation of vapor pressure. OECD does not specifically reject other calculation methods. Comparison of calculated vapor pressures of 11 compounds using the Watson correlation method and using the Advanced Chemistry Development Inc. (ACD) method showed that the ACD results were generally more accurate than the “Watson values”. The vapor pressure of the test substance was calculated with a method that was validated with experimental vapor pressure data that included a wide range of chemical classes including ether, carboxylic acid, carbamate, phenol, halogenated aromatic and aliphatic, and nitro. The vapor pressure was calculated to be 0.05 ± 0.03 Pa at 25 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)