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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
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Diss Factsheets
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EC number: 204-438-5 | CAS number: 120-94-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The log Pow was determined to be 1.1 at 23 °C
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.1
- at the temperature of:
- 23 °C
Additional information
A GLP study was conducted (BASF SE, 14L00166) to determine the partition coefficient octanol /water of the test item. Based on the result of the QSAR estimation as well as the physical and chemical properties of the test item, the HPLC method according to OECD TG 117 was regarded as suitable and was therefore chosen for main test. 7 reference compounds were chosen with a log Pow range of 0.3 to 2.1 to ensure that the estimated logPow of the test item will be covered by the calibration. Two independed measurements of the reference and test item solution were performed. The test was performed at 23 °C. Using linear regression analysis the logPow of the test item was determined to be 1.1 at 23 °C (data refers to the almost not ionised form).
Using QSAR model the logPow of the test item was calculated to decide which method is most suitable for logPow determination. Using EpiSuite software the log Kow of the substances was calculated to be 0.9084 at 25 °C for the uncharged molecule. The substance is within the applicability domain of the model. Thus, the calculated value was regarded as reliable. Based on these result the HPLC method (applicability range logPow 0 - 6) was chosen for main test.
In addition the SRC PhysProp database (Hansch, C. and Leo, A.J. 1995) reports the log Pow to be 0.92 at 25 °C without providing data about the pH value. All available data are in the same range. The experimental determined logPow was regarded as most reliable and was therefore chosen as key value for chemical safety assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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