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EC number: 270-232-7 | CAS number: 68413-60-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity was tested on Bobwhite Quail. The LD50 was above 5000 mg/kg b.w. The LC50 (5d dietary administration) was above 5000 mg/kg food.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for birds:
- 5 000 mg/kg food
Additional information
The toxicity to birds was evaluated in two studies (based on read-across, see IUCLID section 13 for justification):
1. The acute toxicity of FeNaEDTA was studied on Bobwhite quail according to the Guideline OPPTS 850.2100 and SETAC Europe (Leuschner 2008). The test item was administered at a single dose (1000, 2000, 3000 and 5000 mg/kg b.w.) to 5 males and 5 females in each tested dose and control. Animals were observed individually for effects on regurgitation, signs of intoxication and remission, abnormal behaviour, mortality, time of death, body weight and food consumption during 14 days. All surviving birds after the 14 days were sacrified, dissected and inspected macroscopically. The LD50was determined to be > 5000 mg/kg b.w.. Converted to the submission substance the LD50 was >4717 mg/kg b.w..
2. The acute toxicity after oral administration via the diet of five consecutive days to birds was studied in Bobwhite quail. Birds were fed a diet containing FeNaEDTA at a concentration of 5000 ppm. Beginning of on day 6, the birds were fed the basal diet, free of the test item, for 8 additional days. At the end of the study all surviving birds were sacrificed, dissected and inspected macroscopically. Two controls were used. 10 birds were use per dose and per control (total 30 birds). After dosing all animals were observed for signs of intoxication and other abnormal behaviour, mortality, body weight and food consumption. At the end of the experiment all animals were sacrificed, dissected and inspected macroscopically.
No toxic signs were noted after oral administration of FeNaEDTA via the diet at a concentration of 5000 ppm FeNaEDTA (limit test). No test item-related inhibition of body weight gain was observed. No test item-related changes were noted at necropsy.
The LC50was > 5000 ppm, and this corresponds to a LD50> 886.1 mg FeNaEDTA/kg b.w./d (active compound). Converted to the submission substance, the LD50 was >836 mg/kg b.w./day.
Based on the availability of these two short-term studies, on the fact that the mammalian dataset does not indicate acute or chronic toxicity of the test substance and for reasons of animal welfare, testing for long-term reproductive toxicity to birds is waived.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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