Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides

Endpoint summary

Additional information

For each of three trophic levels (fish, Daphnia, and algae) one short-term L(E) C50 is available. Based on the nominal concentrations, the most sensitive acute toxicity of Fatty acids, tall-oil, compounds with N-[3-(dimethylamio)propyl]tall-oil amides is to Daphnia. It was investigated in a semi-static test according to EC NO 440/2008, Method C.2 'Acute toxicity for Daphnia' which is equivalent to OECD Guideline for Testing of Chemicals No. 202 'Daphnia sp., Acute Immobilisation Test'. After 48 hours of exposure an EC50 of 0.111 mg/L was determined by probit analysis, based on results from chemical analysis. According to column 2 of REACH Annex IX, further long-term toxicity tests should be proposed by the registrant if the chemical safety assessment indicates the need to further investigate effects on aquatic organisms as indicated by a PEC/PNEC ratio > 1. Having a PEC/PNEC ratio < 1 for all exposure scenarios, there is no need to perform a long-term assay as the risk towards aquatic organisms is sufficiently controlled based on the already available information. The acute toxicity of Fatty acids, tall-oil, compds. with N-[3 -(dimethylamino)propyl]tall-oil amides to microorganisms in biological treatment plant was investigated in a static test according to ISO 8192 -1986/B "Activated sludge respiration inhibition". After 3 hours of exposure an EC50 of 211 mg/L (nominal) was determined using Probit-analysis.