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Diss Factsheets
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EC number: 622-542-2 | CAS number: 3891-98-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in soil
Administrative data
Link to relevant study record(s)
Description of key information
This study showed that the majority of [14C]Farnesane dissipated over time in all four soils (loam sand (Soil I), silt loam (Soil II and II), or silty clay loam (Soil IV)) at 12°C; the majority of the applied radioactivity was captured in the volatile traps.
Between 14.5% to 20.3% of applied radioactivity remained in the soils on Day 120 as bound radioactivity after all extractions had been carried out. On day 120 the ‘harsh’ extractions removed 0.4, 0.5, 1.3 and 0.7% of the applied radioactivity for soil I, II, III, and IV respectively. Therefore, these residues are not considered to be bioavailable and binding to soils was considered a pathway for disappearance.
Radio-TLC analysis of solvent extractions 1 and 2 showed the applied radioactivity was present as [14C]Farnesane, and no degradation products were detected.
On day 120 mineralisation accounted for 45.6, 38.8, 37.6 and 12.7% of the applied radioactivity in Soil I, II, III, and IV vessels, respectively, therefore Farnesane showed the potential to degrade.
For dissipation kinetic analysis the decline in [14C]Farnesane concentration was deemed to have occurred by degradation or transfer processes and was calculated using soil extracts only; bound residues were not considered to be bioavailable and were considered a method of disappearance. The DT50 was calculated as 5.11, 5.01, 2.82 and 9.39 days for Soil I, II III, and IV vessels, respectively.
For degradation kinetic analysis the decline in [14C]Farnesane concentration was deemed to have occurred by degradation only, bound residues were considered to be 100% parent and not a mechanism for disappearance. The DegT50 was calculated as 7.38, 7.68, 7.05 and 25.8 days for Soil I, II, III, and IV vessels, respectively.
Key value for chemical safety assessment
- Half-life in soil:
- 9.39 d
- at the temperature of:
- 12 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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