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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Lethal concentration 50%: >100 mg/L
Lethal concentration 0%: >100 mg/L

Key value for chemical safety assessment

Additional information

The acute toxicity of 1,4 -Butanediol to freshwater fish has been tested according to various guideline and non-guideline methods under GLP and non-GLP conditions. Test results of a study completed according to OECD Method 203 yield a 96 hr LC50 value of >100 mg/L and a 96 hr LC0 value of >100 mg/L (BASF AG 2005). Additional test results from reliable data sources include a 48 hour LC50 value of 427 mg/L (BASF 1977), and a 24h LC50 value of >5 mg/L (Hollis et al. 1954). These data indicate that 1,4 -Butenediol has a very low degree of toxicity to freshwater fish.