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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 209-400-1 | CAS number: 576-26-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Additional physico-chemical information
Administrative data
Link to relevant study record(s)
Description of key information
2,6-Xylenol is considered to be:
- Not a self-reactive substance;
- Not sensitive to self-ignition; and
- Potentially corrosive to metals.
Additional information
Self-reactive substances or mixtures are thermally unstable liquid or solid substances or mixtures liable to undergo a strongly exothermic decomposition even without participation of oxygen (air). Considering the chemical structure of the substance and taking into account Appendix 6 for self-reactive substances (particularly Tables A6.1 and A6.2) of the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, 2,6-Xylenol is considered not to contain any chemical groups indicating self-reactive properties.
Regarding the potential for self-ignition, and following the ECHA Guidance to regulation (EC) No 1272/2008 on classification, labelling and packing (CLP) of substances and mixtures (2009), substances with a low melting point (less than 160 °C) should not be considered for classification in this hazard class since the melting process is endothermic and the substance-air surface is drastically reduced. This criterion is only applicable if the substance is completely molten up to this temperature. Based on the melting point of 2,6-Xylenol, this substance is not considered to be sensitive to self-ignition.
A substance or a mixture that is corrosive to metals will, by chemical action, materially damage, or even destroy metals. The following substances and mixtures have to be considered for classification as corrosive to metals (ECHA Guidance to regulation (EC) No 1272/2008 on classification, labelling and packing (CLP) of substances and mixtures, 2009): substances and mixtures having acidic or basic functional groups; substances or mixtures containing halogen; substances able to form complexes with metals and mixtures containing such substances.
2,6-Xylenol has an acidic functional group (OH). In general, aromatic alcohols are considered to be slightly acidic. The pKa confirms that 2,6-Xylenol is a very weak acid; the proton will only be released under basic conditions. Based on its skin corrosive properties however, potential corrosivity to metals cannot be ruled-out and hence 2,6-Xylenol should be considered as potentially corrosive to metals.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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