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EC number: 203-453-4 | CAS number: 107-02-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
fruitfly Drosophila melanogaster: 4-h LC50=82.17-406.03 mg/l (exposure to an aqueous solution of acrolein on a petri dish; resultsdepending on the strain and the gender of the animals )
Oryzaephilus surinamensis, Trilobium castaneum, Sitophilus oryzae, and Rhyzopertha dominica (arthropds adult stage):
24h-LC50=1.87 to 6.7 mg/l
arthropds eggs/juvenile stage: 24h LC100=80 mg/l
Key value for chemical safety assessment
Additional information
1. European Union Risk Assessment Report of Acrolein (EU, 2001)
There are no data cited in the European Risk Assessment Report for the toxicity of acrolein to terrestrial arthropods.
2. Agreement with further international Reports and Studies published after finalisation of the EU Risk Assessment Report 2001
None
3. Substantial disagreements in comparison to further international Reports to European Union Risk Assessment Report 2001
None
4. Additional aspects in further international Reports
WHO (2002): A 4-h LC50 exceeding 4606 mg/litre following exposure to an aqueous solution of acrolein on a petri dish is reported for the fruitfly Drosophila melanogaster. A review of the original literature cited in the WHO-reports shows that the 4h-LC50 values are in the range of 82.17 to 406.03 mg/litre, depending on the strain and the gender of the animals.
5. Additional information in newer Studies, not included in the European Union Risk Assessment Report 2001 or further cited international reports
The suitability of acrolein as a fumigation agent to protect stored crops against insects was assessed. Adult animals of the species Oryzaephilus surinamensis, Trilobium castaneum, Sitophilus oryzae, and Rhyzopertha dominica were exposed to acrolein under laboratory conditions in 1150 mL glass jars. Dosages of acrolein were deposited on a blotting paper strip located in the centre of the lid of the test containers. The fumigation was terminated after 24 h, the mortality of the animals was assessed 24h after termination. Two different experiments were made: In an ‘Empty-space test’ animals were exposed in cages that were placed in test containers. In a ‘Penetration test’ the test containers were additionally filled with wheat to simulate storage conditions e.g. in granaries.
In the ‘Empty-space test’ the 24h-LC50 were 1.87 mg/L (O. surinamensis), 6.7 mg/L (T. castaneum), 2.4 mg/L (S. oryzae), and 3.1 mg/L (R. dominica). In the ‘Penetration test’ the 24h-LC50 11.9 mg/L (O. surinamensis), 30.2 mg/L mg/L (T. castaneum), 14.8 mg/L (S. oryzae), and 22.4 mg/L (R. dominica).
In a third test wheat containing eggs, larvae and pupae of S. oryzae and R. dominicawere fumigated in glass jars with acrolein for 24 h. Within 8 weeks after fumigation no adults of S. oryzae and R. dominica emerged from wheat that had been exposed to acrolein at the rate of 80 mg/L.
All effect values are expressed as test concentrations dropped on the blotting paper strips. No information is available about the concentration of fumigated acrolein in the air.
6. Conclusions
The 4-h LC50 for the fruitfly Drosophila melanogaster, which is the only invertebrate tested, exceeded 4606 mg/litre following exposure to an aqueous solution of acrolein on a petri dish. A review of the original literature cited in the WHO-reports shows that the 4h-LC50 values are in the range of 82.17 to 406.03 mg/litre, depending on the strain and the gender of the animals.
The 24h-LC50 in a fumigation test were in the range of 1.87 to 6.7 mg/L for Oryzaephilus surinamensis, Trilobium castaneum, Sitophilus oryzae, and Rhyzopertha dominica. The animals were also fumigated in presence of wheat, the resulting 24h-LC50s were in the range of 11.9 to 30.2 mg/L. Within 8 weeks after fumigation no adults of S. oryzae and R. dominica emerged from wheat containing eggs, larvae and pupae of S. oryzae and R. dominica after fumigation for 24h with 80 mg/L. As no information is available about the concentration of fumigated acrolein in the air (effect values are expressed as test concentrations dropped on the blotting paper strips inserted in the test containers) these results are used for supportive information.
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