Registration Dossier
Registration Dossier
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EC number: 200-198-0 | CAS number: 54-21-7
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- density, other
- Remarks:
- pour and tap density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Data is from experimental study report
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Qualifier:
- according to guideline
- Guideline:
- other: the method recommended in the International Pharmacopoeia, fourth Edition, 2014.
- GLP compliance:
- no
- Type of method:
- pour and tap (for solids)
- Key result
- Type:
- pour density
- Density:
- 0.556 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: No details available
- Key result
- Type:
- tap density
- Density:
- 0.616 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: No details available
- Conclusions:
- The density of test chemical was determined following OECD Guideline 109 and according to the Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014 using bulk density apparatus. The mean pour density and tapped density of test chemical was determined to be 0.5556 g/cm³ and 0.6156 g/cm³at 20 °C and 968.3 hPa.
- Executive summary:
The density of test chemical was determined following OECD Guideline 109 and according to the Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014 using bulk density apparatus. The mean pour density and tapped density of test chemical was determined to be 0.5556 g/cm³ and 0.6156 g/cm³ at 20 °C and 968.3 hPa.
Reference
Description of key information
The density of test chemical was determined following OECD Guideline 109 and according to the Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014 using bulk density apparatus. The mean pour density and tapped density of test chemical was determined to be 0.5556 g/cm³ and 0.6156 g/cm³ at 20 °C and 968.3 hPa.
Key value for chemical safety assessment
- Relative density at 20C:
- 0.556
Additional information
The density of test chemical was determined following OECD Guideline 109 and according to the Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014 using bulk density apparatus. The mean pour density and tapped density of test chemical was determined to be 0.5556 g/cm³ and 0.6156 g/cm³ at 20 °C and 968.3 hPa.
Based on supporting data also determined the bulk density of test chemical by the mass by volume method as 0.56 g/cm3 at room temperature of 25 °C.
Other supporting data from authoritative database Gestis, the density of test chemical was determined to be 0.32 g/cm³.
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