Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 209-909-9 | CAS number: 597-82-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Note: The substance is currently under evaluation as part of the Community Rolling Action Plan 2016 (Member State: The Netherlands). Studies required in the final decision are ongoing.
Short-term toxicity tests for three trophic levels are available. No toxic effects occur at the range of water solubility. All available acute tests show that the substance does not exert adverse effects to aquatic organisms up to the limit of solubility in water (0.020 mg/L at 20 °C, BASF 2013).
One long-term toxicity study on daphnids with O,O,O-triphenyl phosphorothiate is available (BASF, 2021). In the key study a stock solution was prepared using a solid-liquid (slow-stir) saturator technique to achieve the saturation concentration of 7.24 µg/L. No significant mortality or any other additional significant adverse effects or abnormal behavior were observed in any of the test treatments. The test substance did not have a chronic toxic effect on Daphnia magna up to the saturation concentration of 7.24 μg/L.
A chronic toxicity study on daphnids according to OECD guideline 211 under considering the OECD no 23 guidance document was performed with O,O,O-triphenyl phosphorothioate in a lower purity ( > 25%; BASF 2015). The test showed no effects up to the saturation concentration (undiluted filtrate with a loading rate of 5.5 mg/L (WAF)). Based on these data it can be expected that the 21d-NOEL is higher than the saturation concentration using a loading rate of 1 mg/L (WAF). Furthermore, in a BCF study performed with the substance of lower purity (> 25%) no adverse effects on fish were observed during 56 days of exposure in concentrations within the solubility range of the test substance (Gakushuin University 1999). The test concentrations of the test substance were verified in this test.
In a 3h acute toxicity study sewage sludge micro-organisms were exposed to the test item at nominal concentrations of 100 mg/L in accordance with OECD guideline 209 (Ciba-Geigy 1988). The IC50 value based on respiration rate was > 100 mg/L after a 3h contact time. No effects were observed up to the highest test concentration of 100 mg/L (nominal). A study with O,O,O-triphenyl phosphorothioate in a lower purity (purity > 25%) supports this results. In this acute toxicity study sewage sludge micro-organisms were exposed to the test item at nominal concentrations of 1000 mg/L for 3h in accordance with OECD guideline 209 (RCC 1997). The IC50 value based on respiration rate was > 1000 mg/L after a 3h contact time. The NOEC was 320 mg/L.
Based on the available data on aquatic toxicity it can be stated that the substance is neither acutely harmful nor harmful at chronic exposure up to its limit of solubility in water. The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.