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Diss Factsheets
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EC number: 237-396-1 | CAS number: 13770-89-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary literature source
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Summary Tables of Biological Tests
- Author:
- National Research Council Chemical-Biological Coordination Center
- Year:
- 1 952
- Bibliographic source:
- 4: 320
- Reference Type:
- secondary source
- Title:
- Registry of Toxic Effects of Chemical Substances: Nickel (II) sulfamate
- Author:
- National Institute for Occupational Safety and Health
- Year:
- 2 008
- Bibliographic source:
- RTECS #QR9275000
Materials and methods
- Principles of method if other than guideline:
- Study design not reported
- GLP compliance:
- not specified
- Limit test:
- no
Test material
- Reference substance name:
- Nickel bis(sulphamidate)
- EC Number:
- 237-396-1
- EC Name:
- Nickel bis(sulphamidate)
- Cas Number:
- 13770-89-3
- Molecular formula:
- Ni(NH2SO3)2
- IUPAC Name:
- nickel(2+) disulfamate
- Details on test material:
- - Name of test material (as cited in study report): nickel (II) sulfamate
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- Not Reported
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- other: isotonic saline
- Details on exposure:
- Not Reported
- Doses:
- 500, 250, 125, 62.5, 31.3 mg/kg
- No. of animals per sex per dose:
500 mg/kg: 5
250 mg/kg: 3
125 mg/kg: 3
62.5 mg/kg: 3
31.3 mg/kg: 3
(sex not reported)- Control animals:
- not specified
- Details on study design:
- Not Reported
- Statistics:
- Not Reported
Results and discussion
- Mortality:
- 500 mg/kg: 5/5 (day of death: 1 animal at 5 minutes, 3 at 15 minutes, one at 3 days)
250 mg/kg: 2/3 (day of death: day 3 for both animals)
125 mg/kg: 0/3
62.5 mg/kg: 0/3
31.3 mg/kg: 0/3 - Clinical signs:
Animals in the high dose group (500 mg/kg) exhibited dyspnea and straining- Body weight:
- Not Reported
- Gross pathology:
- Not Reported
- Other findings:
- Not Reported
Any other information on results incl. tables
Not Applicable
Applicant's summary and conclusion
- Conclusions:
Not Applicable (data insufficient)- Executive summary:
STUDY RATED BY AN INDEPENDENT REVIEWER
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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