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Diss Factsheets
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EC number: 290-754-9 | CAS number: 90218-76-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1996-12-13 to 1997-01-30
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Deviations:
- yes
- Remarks:
- Composition of medium: according to OECD guideline, sole deviation: pH 7.5 of solution 1
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: secondary effluent from a predominantly domestic sewage plant
- Details on inoculum:
- - Source of inoculum/activated sludge: public sewage treatment plant Plön, Germany
- Laboratory culture: no
- Storage conditions: keeping under aerobic conditions
- Storage length: not mentioned
- Preparation of inoculum for exposure: The inoculum was filtered through a coarse filter, the first 200 ml being discarded.
- Pretreatment: none
- Concentration of sludge: not mentioned
- Initial cell/biomass concentration: not measured
- Water filtered: not mentioned - Duration of test (contact time):
- 48 d
- Initial conc.:
- 20 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to OECD guideline, sole deviation: pH 7.5 of solution 1
- Additional substrate: none
- Solubilising agent (type and concentration if used): not used
- Test temperature: as close as possible to 20°C, no further measurements mentioned
- pH: 7.70 pH of medium, no further meassurements mentioned
- pH adjusted: no
- Aeration of dilution water: yes
- Suspended solids concentration: not determined
- Continuous darkness: yes, or only diffuse light
- Other: none
TEST SYSTEM
- Culturing apparatus: test bottles, no further details mentioned
- Number of culture flasks/concentration: 2 bottles, one concentration
- Method used to create aerobic conditions: not mentioned
- Method used to create anaerobic conditions: not applicable
- Measuring equipment: titration with HCl 0.05 M using phenolphthalein as indicator
- Details of trap for CO2: 3 flasks containing 100 ml 0.0125 M barium hydroxide in a serial order
- Other: none
SAMPLING
- Sampling frequency: on days 2, 4, 7, 10, 14, 18, 24, 28, 31, 35, 40, 47, and 48
- Sampling method: On the day of measurement the barium hydroxid absorber was disconnencted closest to the flask and the solution was titrated. The remaining absorbers were moved one place closer to the flask and a new absorber was placed containing 100 ml fresh 0.0125 M barium hydroxid at the far end of the series.
- Sample storage before analysis: not mentioned
- Other: none
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes (2 vessels with inoculum without test substance)
- Abiotic sterile control: not performed
- Toxicity control: not performed
- Other: none
STATISTICAL METHODS: no statistics performed - Reference substance:
- acetic acid, sodium salt
- Remarks:
- 51.33 mg/L final test medium (15 mg DOC/L)
- Preliminary study:
- not performed
- Test performance:
- Parallel groups of bottles were prepared for the determination of the test and reference chemical in simultaneous experimental series. The test was conducted in duplicate in a parallel series.
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 20.7
- Sampling time:
- 28 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 71.4
- Sampling time:
- 48 d
- Details on results:
- see below
- Results with reference substance:
- see below
- Validity criteria fulfilled:
- yes
- Remarks:
- Difference of extremes of replicate values was less than 20% and the percentage degradation of reference control reached the level for ready biodegradability by 14 days.
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- Under the present test conditions, 71.4 % biodegradability was determined for 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters at 48 days (20.7 % biodegradability at 28 days).
- Executive summary:
The purpose of this test was the measurement of the biodegradability of 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters in an aerobic, aqueous medium at a concentration of 10 - 20 mg DOC or TOC/L.
The study was conducted according to the OECD guideline 301B and the EEC guideline L383 A: C.4 -C.
A measured volume of inoculated mineral medium containing a known concentration of the test chemical (14.8 mg TOC/L) as the nominal sole source of organic carbon was aerated by the passage of carbon dioxide-free air at a controlled rate in the dark or in diffuse light. Degradation was followed over 48 days by determining he carbon dioxide produced, which was trapped in barium hydroxide and which was measured by titration of the residual hydroxide. The amount of carbon dioxide produced from the test chemical (corrected for that derived from the blank inoculum) was expressed as a percentage of ThCO2.
Under the present test conditions, 20.7 % biodegradability was determined for 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters at 28 days (71.4 % biodegradability at 48 days).
Reference
Table: Degradation kinetic
sampling time [days] | degradation [%] | |||
test substance | reference substance | |||
vessel 1 | vessel 2 | mean | ||
2 | -0.1 | 0.1 | 0.0 | 16.3 |
4 | -0.1 | 0.4 | 0.2 | 34.0 |
7 | 0.3 | 1.3 | 0.7 | 50.4 |
10 | 0.9 | 2.0 | 1.5 | 63.8 |
14 | 1.6 | 3.2 | 2.4 | 71.9 |
18 | 2.7 | 4.7 | 3.7 | 74.1 |
24 | 7.4 | 6.9 | 7.2 | 78.3 |
28 | 22.6 | 18.7 | 20.7 | 79.1 |
31 | 35.2 | 33.2 | 34.2 | 79.8 |
35 | 46.0 | 45.1 | 45.6 | 80.5 |
40 | 55.3 | 57.3 | 56.3 | 80.3 |
47 | 63.8 | 68.6 | 66.2 | 80.5 |
48 | 67.3 | 73.1 | 70.2 | 81.6 |
48# | 68.7 | 74.1 | 71.4 | 81.6 |
# analysis of the second and third trap
Description of key information
71.4 % biodegradability was determined for 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters at 48 days (20.7 % biodegradability at 28 days).
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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