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Diss Factsheets
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EC number: 256-032-2 | CAS number: 42978-66-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish: With high probability acutely toxic to fish.
Key study: BASF AG (1988, report no. 10F0158/885179). DIN 38412-15, Leuciscus idus:
- 96-h LC50 = 4.6 – 10 mg/L (nom.)
Long-term toxicity data to fish: no data available.
no data available. Information requirement waived based on the results of the chemical safety assessment (no PBT/vPvB; RCR < 1).
Short term toxicity to aquatic invertebrates:With high probability acutely harmful to aquatic invertebrates.
Key study: BASF AG (1988, report no. 1/0671/2/88-0671/88): EU method C.2, Daphnia magna:
48-h EC50 = 89 mg/L (nom.)
Long-term toxicity to aquatic invertebrates:no data available. Information requirement waived based on the results of the chemical safety assessment (no PBT/vPvB; RCR < 1).
Toxicity to aquatic algae and cyanobacteria: Acutely toxic to aquatic algae.
Key study: BASF AG (1988, report no. 88/0671): DIN 38412 p. 9, Desmodesmus subspicatus:
72-h ErC50 = 65.9 mg/L (nom.)
72-h ErC10 = 6.6 mg/L (nom.)
Toxicity to aquatic microorganisms: The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Weight-of-evidence - 30 -min EC 50 > 1000 mg/L:
TPGDA (CAS 42978-66-5): short-term respiration inhibition study (Robra), Pseudomona putida (BASF AG, 1988, rep.no.: 01/88/0671):
30 -min EC10 > 10000 mg/L (nom.), EC50 > 10000 mg/L (nom.)
Structurally similar substance CAS 57472-68-1: short-term respiration inhibition study according to OECD 209, domestic activated sludge (GLP; BASF AG, 2002, rep. no.: 02/0368/08/1)
30-min EC20 > 1000 mg/L (nom.)
Conclusion:Based on the available experimental data, TPGDA (CAS 42978-66--5) is considered to be acutely toxic to aquatic organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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