(R)-p-mentha-1,8-diene

Density

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

August 2010

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

Study performed according to international guidelines but not under GLP and with some lack of details.

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

not specified

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

not specified

GLP compliance:

no

Type of method:

oscillating densitimeter

Key result

Type:

relative density

Density:

0.844

Temp.:

20 °C

Remarks on result:

other: relative density at 20 °C in reference with water at 4 °C

The obtained value is the mean result of three determinations at 20 ± 0.5 °C :

Assay No.	Density (kg/m3)	Relative density
1	844.1	0.8441
2	844.0	0.8440
3	844.1	0.8441
Mean ± standard deviation	844.1 ± 0.1	0.8441 ± 0.0001

Relative density = density (kg/m3) / 999.975 (kg/m3) (density of water at 4°C).

The average density at 20°C ± 0.5 °C of the test item is 844 ± 1 kg/m3.

Conclusions:

The relative density at 20°C/4°C of D-LIMONENE (5989-27-5) is 0.844 ± 0.001.

Executive summary:

The relative density of D-LIMONENE has been measured according to OECD Guideline 109 and to EU Method A.3.

Using an oscillating densimeter, the relative density of the test item at 20°C in reference with water at 4°C (D20/4) was determined as 0.844 ± 0.001.

The result has been considered as reliable with restrictions because the test was performed in complinace with edicted guidelines giving scientifically valid results but some details are lacking in the report (no GLP, no report number, criteria of validity of the results not given).

Reference 2

Endpoint:

density

Remarks:

density

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2005

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

documentation insufficient for assessment

Remarks:

Documentation insufficient for assessment: no certificate of analysis of the test substance, no details on methodology

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to other study

Principles of method if other than guideline:

Method: Density measured using Anton Paar (DMA58) densimeter

GLP compliance:

not specified

Type of method:

other: densimeter

Type:

density

Density:

0.837 g/cm³

Temp.:

298.15 K

None

Conclusions:

The density of (+)-limonene was measured to be 0.83731 g/cm3 at 298.15 K.

Executive summary:

A study was conducted to determine the density of (+)-limonene using Anton Paar (DMA58) densimeter.

The density of (+)-limonene was measured to be 0.83731 g/cm3 at 298.15 K.

Reference 3

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

no data

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to other study

Principles of method if other than guideline:

Method followed unknown, data from handbook

GLP compliance:

not specified

Type of method:

other: no data

Type:

relative density

Density:

0.84

Temp.:

21 °C

Remarks on result:

other: relative density at 21 °C against water at 4 °C

None

Conclusions:

The relative density D21/4 of d-limonene is 0.8402.

Executive summary:

The relative density of d-limonene was reported in the Merck Index 2006 as 0.8402 at 21 °C against water at 4 °C.

The reliability of this result has been considered as 2 (reliable with restrictions) because ‘The Merck Index’ is cited as a reference book containing peer reviewed data in the REACH Guidance Document R.7a.

Reference 4

Endpoint:

relative density

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Justification for type of information:

D-Limonene is one of the two isomers of dipentene. Therefore, data on dipentene can be used for extrapolation to d-limonene. See read-across justification document in section 13.

Reason / purpose for cross-reference:

read-across source

Type:

relative density

Density:

0.84

Temp.:

20.85 °C

Remarks on result:

other: relative density against water at 4 °C

None

Conclusions:

The relative density D20.85/4 of dl-limonene is 0.8402.

Executive summary:

The relative density of dl-limonene was reported in the Merck Index 2006 as 0.8402 at 20.85 °C against water at 4 °C.

The reliability of this result has been considered as 2 (reliable with restrictions) because ‘The Merck Index’ is cited as a reference book containing peer reviewed data in the REACH Guidance Document R.7a.

Reference 5

Endpoint:

relative density

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Justification for type of information:

L-Limonene is the S-isomer of d-limonene. Therefore, data on l-limonene can be used for extrapolation to d-limonene. See read-across justification document in section 13.

Reason / purpose for cross-reference:

read-across source

Principles of method if other than guideline:

Method followed unknown, data from handbook

Type:

relative density

Density:

0.841

Temp.:

20.5 °C

Remarks on result:

other: relative density against water at 4 °C

None

Conclusions:

The relative density D20.5/4 of l-limonene is 0.8407.

Executive summary:

The relative density of l-limonene was reported in The Merck Index 2006 as 0.8407 at 20.5 °C against water at 4 °C.

The reliability of this result has been considered as 2 (reliable with restrictions) because ‘The Merck Index’ is cited as a reference book containing peer reviewed data in the REACH Guidance Document R.7a.

Description of key information

The relative density of D-LIMONENE at 20 °C (D20/4) is 0.844 ± 0.001.

Key value for chemical safety assessment

Relative density at 20C:

0.844

Additional information

The relative density of D-LIMONENE at 20°C in reference with water at 4°C was determined in a study performed according to OECD guideline 109 and EU method A3 using an oscillating densimeter. The value was considered with a reliability of 2 (reliable with restrictions) because the result is scientifically acceptable but not obtained under GLP and some details were lacking in the report. However the relative density is valid as key value and supported by several studies measuring density or relative density of d-, l- or dl-limonene at different temperatures.