Registration Dossier
Registration Dossier
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EC number: 203-631-1 | CAS number: 108-94-1
Endpoint summary
Administrative data
Description of key information
A guinea pig maximization test (Bruze et al., Contact Dermatitis, 1988) showed a sensitizing effect in one of two batches of a Cyclohexanone resin tested. The same authors also conducted a GPMT with pure Cyclohexanone which showed negative results. A mouse ear swelling test, a guinea pig maximization test and a Buehler test (Gad et al., 1986) showed no skin sensitizing properties for Cyclohexanone.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
As pure Cyclohexanone showed no sensitising properties in any of the tests available, classification is not warranted.
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