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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
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Diss Factsheets
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EC number: 242-449-7 | CAS number: 18621-94-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
The lithium salts of dicarboxylic acids (C6 - C10) are readily biodegradable.
A risk assessment under the high production volume program that includes the lithium salts of dicarboxylic acids (C6 - C10) as part of a wider aliphatics acids category (CoCAM 2014) concludes that ‘the weight of evidence indicates that the aliphatics acid category members are readily biodegradable’. They share a common degradation pathway in which they are degraded to acetyl-Co A or other key metabolites in all living systems and differences in metabolism or biodegradation of even or odd numbered carbon chain compounds are not expected.
The lithium salts of fatty acids are expected to dissociate to lithium ions and acids. As an inorganic metal, the lithium ion will not undergo biodegradation, however, the acid component will be biodegraded. Adipic acid is readily biodegradable based on publicly available data from five ready biodegradation tests. Data on biodegradation are read across from adipic acid to lithium salts of fatty acids (C6-C10) based on structural similarity and also on the conclusions of the CoCAM (2014) report. Therefore, the lithium salts of fatty acids (C6-C10) are all readily biodegradable.
This conclusion is supported by data on dilithium glutarate (C5), which shows that the substance is readily biodegradable, reaching 50% degradation on day 3 and 94% degradation by day 28 of an OECD 301F manometric respirometry test (see dissemination portal). A ready biodegradation test is currently ongoing with dilithium sebacate (C10) to provide data on longer chain length category members as well.
CoCAM. 2014. SIDS initial assessment profile. CoCAM 6 September 30- October 3, 2014
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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