Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
Exploring QSAR - Hydrophobic, Electronic, and Steric Constants
Author:
Hansch, C., Leo, A., D. Hoekman.
Year:
1995
Bibliographic source:
Washington, DC: American Chemical Society., 1995., p. 6 . cited in HSDB 01.May2007

Materials and methods

Test guideline
Guideline:
other: no data
Principles of method if other than guideline:
Method: other (measured)
GLP compliance:
not specified
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Propionic acid
EC Number:
201-176-3
EC Name:
Propionic acid
Cas Number:
79-09-4
Molecular formula:
C3H6O2
IUPAC Name:
propionic acid
Details on test material:
- Name of test material (as cited in study report): propionic acid
- Analytical purity: pure

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
0.33

Any other information on results incl. tables

No experimental values for the temperature and pH are available. The standard programm usualy calculates these values at 25°C and for the uncharged molecules. The pH value for these substance is around 2,5. For these reasons it has been assumed, because the experimental and calculated values are quite close, it can be inferred that the molecule is nearly uncharged and therefore the experimental value can regarded as sufficient valid.

Applicant's summary and conclusion