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Diss Factsheets
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EC number: 484-360-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 06-09, 2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study has been performed according to ISO guidelines and according to GLP principles.
- Principles of method if other than guideline:
- ISO 14669 (1998): Water Quality - Determination of acute
lethal toxicity to marine copepods (Copepoda, Crustacea).
OECD 2000: Guidance Document on aquatic toxicity testing of
difficult substances and mixtures. OECD Environmental Health
and Safety Publications Series on Testing and Assessment
No. 23. ENV/JM/MONO(2000)6.
ISO 8245: Water Quality - Guidelines for the determination
of total organic carbon (TOC) and dissolved organic carbon
(DOC). - GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on test solutions:
- Identity and concentration of auxiliary solvent for dispersal: Species: the marine crustacean Acartia tonsa.
Test medium: natural seawater (salinity adjusted by
distilled water to 32 S).
Reference substance: 3,5-dichlorophenol
Separate WAF's were prepared for 5 loading rates (101-180-
321-561-1000 mg/l) in the dark at 21°C. After 23 h WAF's
were filtered through Wathman GF/C glass fibre filters to
remove non-settling suspended material. - Test organisms (species):
- other aquatic crustacea: Acartia tonsa
- Test type:
- static
- Water media type:
- saltwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 34.8 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- other: TOC
- Basis for effect:
- mortality
- Remarks on result:
- other: WAF loading was 1000 mg/l
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 48 hour EC50 of Radiagreen EBL (Pentaerythritol mono oleate base Polyol) is estimated as greater than 1000 mg/l. The highest no-observed (lethal) effect concentration (NOEC) was estimated as 1000 mg/l.
Reference
Comments:
TOC analysis:
control seawater: 1.0 mg TOC/l
101 mg/L WAF: 4.8 mg TOC/l
1000 mg/l WAF: 34.8 mg TOC/l
The results show that a portion of the test substance
partitioned to the water phase as dissolved organic matter.
Assuming that the carbon content of the test substance is
70% by weight, approximately 5% of the added substance was
present in the WAF's.
The acute lethality was less than 10% at loading rates up to
1000 mg/l.
Description of key information
The study was performed according to ISO Guideline 14669 and GLP principles.
Key value for chemical safety assessment
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 34.8 mg/L
Additional information
The acute toxicity of Radiagreen EBL (Radia 7853) to the marine crustacean Acartia tonsa has been investigated. The test was performed according to ISO 14669: Determination of acute lethal toxicity to marine copepods (Copepoda, Crustacea). The test was performed on water accommodated fractions (WAF) of the test substance. The loading rates were 100 – 1000 mg/l. The Acartia tonsa were exposed for 48 hours at 20 ±1 °C. Mortality was recorded after 24 and 48 hours. The acute lethality of the substance on the marine copepod Acratia tonsa was less than 10% at loading rates up to 1000 mg/l in acoomodated fractions. Based on analysis of TOC, this results in a 48 -h EC50 of > 34.8 mg/l, and therefore also beyond the water solubility limit.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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