Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 250-317-5 | CAS number: 30737-19-0
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Original citation not found, but figures used for assessment by other regulatory agencies in Europe and US
Note that the concluded toxicity contradicts the CLP Annex VI classification for oxalic acid.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- U.S. National Toxicology Program acute toxicity studies for Oxalic acid
- Author:
- PAN Pesticide Database, Pesticide Action Network,
- Year:
- 2 016
- Bibliographic source:
- Kegley, S.E., Hill, B.R., Orme S., Choi A.H., PAN Pesticide Database, Pesticide Action Network, North America (Oakland, CA, 2016), http:www.pesticideinfo.org. © 2000-2016 Pesticide Action Network, North America. All rights reserved.
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- not specified
- Remarks:
- Performed at academic research institute. Re-testing on animals to GLP is not ethical
Test material
- Reference substance name:
- Oxalic acid
- EC Number:
- 205-634-3
- EC Name:
- Oxalic acid
- Cas Number:
- 144-62-7
- Molecular formula:
- C2H2O4
- IUPAC Name:
- oxalic acid
- Test material form:
- solid: crystalline
Constituent 1
Test animals
- Species:
- rat
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 20 000 mg/kg bw
- Based on:
- act. ingr.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Not conisdered harmful under the conditions used.
- Executive summary:
Original citation not found, but figures used for assessment by other regulatory agencies in Europe and US
Note that the concluded toxicity contradicts the CLP Annex VI classification for oxalic acid (perhaps based on data from tests with local damage from the acid?), but this classification can be disregarded for the assessment of the chromium oxalate that is of low irritancy.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
