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EC number: 219-529-5 | CAS number: 2455-24-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
THFMA is reported to be a colourless to slightly yellowish liquid at 20°C and 1013 hPa and has an ester-like odour (visual and olfactory assessment during test on physicochemical properties (melting point/boiling point)).
THFMA is reported to undergo glass transition (amorphous solidification) at -113°C (determined according to OECD guideline 102, adopted 27th July 1995, and EU Method A.1, December 1992; differential scanning calorimetry).
Theboiling point of THFMA is reported to be 222°C at 1020 hPa (determined according to OECD guideline 103, adopted 27th July 1995 and EU Method A.2, December 1992; differential scanning calorimetry).
The relative density of THFMA is reported to be 1.042 (determined according to DIN51757; oscillating densitimeter).
In accordance with column 2 of REACH regulation annex VII, a granulometry test does not need to be conducted as the substance is a liquid.
The vapour pressure of THFMA is reported to be 0.27 mbar at 20°C (no details on method).
The n-Octanol/Waterpartition coefficient (log Kow) of THFMA was determined according to OECD Guideline 117 (2004) and EU method A.8 (2008) using the HPLC method. The log Kow was 1.76 ± 0.08 at 22.6°C.
The water solubility of THFMA is reported to be 18990 mg/L at 20°C (determined according to OECD guideline 105, adopted 27 July 1995 and EU method A.6, December 1992; flask method).
In accordance with column 2 of REACH regulation annex VII, surface tension testing does not need to be conducted. Based on structure, no surface activity is expected. The test substance is not used as detergent.
The flash point of THFMA is reported to be 99°C at 1013.25 hPa (determined according to EU method A.9, December 1992; Pensky-Martens closed cup method).
The auto-ignition temperature of THFMA was determined according to EU test method A.15, 30 May 2008, and DIN 51794). The auto-ignition temperature of THFMA is reported to be 240°C at 999.8 to 1007.3 hPa.
According to REACH Regulation (Annex XI, 1.), the study on flammability does not need to be conducted if the available data are sufficient for assessment. For THFMA, tests on flash point and auto-ignition are available. Pyrophoricity and flammability on contact with water are not expected based on a consideration of the structure of the substance.
In accordance with column 2 of REACH regulation annex VII, explosive properties testing does not need to be conducted as there are no chemical groups associated with explosive properties in the molecule.
In accordance with column 2 of REACH regulation annex VII, oxidising properties testing does not need to be conducted on the basis of chemical structure.
The kinematic viscosity of THFMA was determined with a micro-Ubbelohde viscometer at 20°C and 40°C (according to OECD guideline 114, adopted 12 May 1981, and DIN 51562).
Kinematic viscosity at 20°C: 2.74 mm²/s
Kinematic viscosity at 40°C: 1.84 mm²/s
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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