Registration Dossier
Registration Dossier
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EC number: 205-159-1 | CAS number: 134-84-9
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1976
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Only results given (methodical details are missing)
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 984
- Report date:
- 1984
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Toxicity test for bulk chemicals to meet DOT regulations (April 24, 1973)
- GLP compliance:
- no
- Remarks:
- Data from 1976 (at this time GLP was not compulsory)
Test material
- Reference substance name:
- Benzophenone
- EC Number:
- 204-337-6
- EC Name:
- Benzophenone
- Cas Number:
- 119-61-9
- Molecular formula:
- C13H10O
- IUPAC Name:
- benzophenone
- Details on test material:
- not further specified
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
- Details on test animals or tissues and environmental conditions:
- not further specified
Test system
- Vehicle:
- not specified
- Controls:
- not specified
- Amount / concentration applied:
- not further specified
- Duration of treatment / exposure:
- not further specified
- Observation period (in vivo):
- not further specified
- Number of animals or in vitro replicates:
- not further specified
- Details on study design:
- not further specified
Results and discussion
In vivo
Results
- Irritation parameter:
- other: The treatment caused no eye irritation.
- Remarks on result:
- no indication of irritation
- Irritant / corrosive response data:
- The treatment caused no eye irritation.
Any other information on results incl. tables
The treatment caused no eye irritation.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The treatment caused no eye irritation.
- Executive summary:
In this study with rabbits the application of benzophenone caused no eye irritation. Thus benzophenone is not subject of classification.
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