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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Endpoint summary
Administrative data
Description of key information
The toxic effect of the test item 2,2’-(C12-14 evennumbered alkylimino) diethanol to Daphnia magna was assessed in a semi-static concentration-response test. The 48-hour NOEC was calculated to be 449 μg test item/L. The 48-hour LOEC was calculated to be 1064 μg test item/L and the 48-hour EC50 value was calculated to be 910 μg test item/L.
The initial concentrations and the maintenance of the exposure concentrations during the test were verified in the analytical part. All reported results refer to time-weighted average concentrations of the test item (weighted sum of time-weighted average values of both measured main ingredients) since the concentrations of the main ingredients were not within ± 20% of the nominal concentrations during the test for all test concentrations and different recovery decrease was determinable for each ingredient.
The influence of 2,2’-(C12-14 evennumbered alkylimino)diethanol on the growth of the freshwater green algae Pseudokirchneriella subcapitata was assessed in a static concentration-response test. The 72-hour EyC50 was calculated to be 3.51 μg test item/L (initial mean: 5.02 μg test item/L) and the 72-hour ErC50 value was calculated to be 6.13 μg test item/L (initial mean: 37.2 μg test item/L). The 72-hour NOEyC was determined to be 2.13 μg test item/L (initial mean: 1.97 μg test item/L) and the associated 72-hour LOEyC was 3.92 μg test item/L (initial mean: 5.47 μg test item/L). The 72-hour NOErC was determined to be 2.13 μg test item/L (initial mean: 1.97 μg test item/L) and the associated 72-hour LOErC was 3.92 μg test item/L (initial mean: 5.47 μg test item/L).
The initial concentrations and the maintenance of the exposure concentrations during the test were assessed in the analytical part. All reported results refer to geometric mean measured concentrations of the test item (weighted sum of geometric mean values of both measured main ingredients) since the concentrations of the main ingredients were not within ± 20% of the nominal concentrations during the test for all test concentrations and different recovery decrease was determinable for each ingredient. In addition, all results were evaluated based on initial mean measured concentrations to compensate varying intermediate recoveries that were determined and to reflect actual dosage of the test item.
In conclusion, the effect concentrations based on inital mean measured concentrations are more realistic to derive the toxicity of the registration substance as they reflect the dissolved amount of substance in combination with the still bioavailable amount adsorbed to algae cells.
The registration substance is readily biodegradable.
From the available data the following worst case CLP-classification is derived:
Aquatic acute 1, M1 ; Aquatic chronic 1, M10
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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