Registration Dossier
Registration Dossier
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EC number: 240-715-7 | CAS number: 16669-59-3
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- See attached full study report
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 971
- Report date:
- 1971
Materials and methods
Test guideline
- Guideline:
- other: unknown
- GLP compliance:
- not specified
Test material
- Reference substance name:
- N-[(2-methylpropoxy)methyl]acrylamide
- EC Number:
- 240-715-7
- EC Name:
- N-[(2-methylpropoxy)methyl]acrylamide
- Cas Number:
- 16669-59-3
- Molecular formula:
- C8H15NO2
- IUPAC Name:
- N-[(2-methylpropoxy)methyl]acrylamide
- Test material form:
- liquid
- Details on test material:
- A clear, light yellow, slightly viscous liquid with a pungent odour
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- unchanged (no vehicle)
Results and discussion
In vivo
Results
- Irritation parameter:
- other: no data
- Basis:
- mean
- Time point:
- 24 h
- Score:
- 8.1
- Max. score:
- 30
- Reversibility:
- fully reversible
- Remarks on result:
- positive indication of irritation
Applicant's summary and conclusion
- Interpretation of results:
- Category 2 (irritating to eyes) based on GHS criteria
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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