Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 211-706-5 | CAS number: 688-74-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://poisoncentres.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- other: experimental study on hydrolysis product Boric acid
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- flask method
- Water solubility:
- 49.2 g/L
- Temp.:
- 20 °C
- pH:
- 3.7
- Details on results:
- Preliminary solubility test
The estimated water solubility is approximately 8.29 g/L. This value means that the shake-flask method had to be applied. Because of the theoretical water solubility (47 g/L) the water solubility test was performed using the theoretical value.
The mean value of the water solubility of Test 1, 2 and 3 is 49.20 ± 0.35 g/L. - Conclusions:
- The water solubility of the test substance was 49.20 ± 0.35 g/L at 20.0 ± 0.5 ºC.
Interpretation of results: very soluble (> 10000 mg/L). - Endpoint:
- water solubility
- Type of information:
- other: experimental study on hydrolysis product n-Butanol
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- according to guideline
- Guideline:
- other: no data
- Principles of method if other than guideline:
- The information does not come from a test report and the minimum fields cannot be filled in.
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Key result
- Water solubility:
- 77 g/L
- Temp.:
- 20 °C
- Remarks on result:
- other: pH unknown
- Conclusions:
- 77 g/L at 20°C
- Executive summary:
According to the 'Handbook of Environmental Fate and Exposure Data for Organic Chemicals, Volume II, Solvents', the water solubility of Tributyl borate is 77 g/L (at 20°C).
No further experimental details are reported in the handbook.
- Endpoint:
- water solubility
- Type of information:
- other: experimental study on hydrolysis product n-Butanol
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: data from well documented publication
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPPTS 830.7860 (Water Solubility Generator Column Method)
- Principles of method if other than guideline:
- Details of the generator column:
- It consists of a 20-cm section of 6-mm o.d. Pyrex tubing joined to a short section of 9-mm o.d. Pyrex tubing. The 6-mm o.d. section of the column was packed with 100-120 mesh Chromosorb W-HP (solid support) which was held in place by two plugs of silanized glass wool. The column was thermostated at 25.0 ± 0.1 °C by pumping water from a constant-temperature bath through a jacket enclosing column.
- The column was coated with a liquid solute by pulling approximately 2 mL of the liquid through the clean, dry support with gentle suction.
- The aqueous phase of the solute was generated by pumping water into the inlet of the coated generator column either by using a minipump or by means of a water reservoir using compressed air at 5 psi.
- Analysis of the aqueous phase from the pure solute coated column yielded the aqueous solubility. - GLP compliance:
- not specified
- Type of method:
- other: Generator Column Method
- Water solubility:
- 63.3 g/L
- Temp.:
- 25 °C
- Remarks on result:
- other: pH unknown
- Details on results:
- The reported water solubility is an average of at least three measurements.
- Conclusions:
- 63.2 g/L at 25°C
- Executive summary:
According to a well documented publication (Tewari Y.B. et al, 1982), the water solubilty of Tributyl borate is 63.2 g/L (at 25°C). The measurement was performed with a modified Generator Column Method.
Referenceopen allclose all
Solubility (shake flask method): Test number, stirring time, Tyndall value and the water solubility of the test substance at 20 ºC:
Test number |
Stirring time (h) |
pH |
Tyndall |
Water solubility (g/L) |
1 |
24 |
3.75 |
0.0020 (0.0018) |
48.86 |
2 |
48 |
3.54 |
0.0031 (0.0020) |
49.57 |
3 |
72 |
3.98 |
0.0022 (0.0021) |
49.16 |
The value between parentheses is Tyndall value of the blank.
Description of key information
Study scientifically not necessary because tributyl borate is rapidly hydrolyzed to boric acid and n-butanol in the presence of water:
- water solubilty of boric acid: 49.2 g/L (at 20°C)
- water solubilty of n-butanol: 77 g/L at 20°C (handbook data) and 63.2 g/L at 25°C (data from publication); key value (arithmetic mean of the two available values) ca. 70 g/L at 20°C
Key value for chemical safety assessment
- Water solubility:
- 70 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)