Registration Dossier
Registration Dossier
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EC number: 220-605-5 | CAS number: 2834-84-6
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- other: visual observation
Test material
- Reference substance name:
- Guanidinium phosphate (1:1)
- EC Number:
- 226-551-9
- EC Name:
- Guanidinium phosphate (1:1)
- Cas Number:
- 5423-22-3
- Molecular formula:
- CH5N3.H3O4P
- IUPAC Name:
- Guanidium phosphate (1:1)
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- > 0.95 - < 1 g/cm³
- Temp.:
- 25 °C
- pH:
- >= 3.56 - <= 4.32
- Remarks on result:
- other: visually assessed
Any other information on results incl. tables
The concentrations of the prepared solutions used to visually determine the water solubility of the test substance are shown in the table hereunder:
| Sample weight (g) | Soluble (visual observation)? | Nominal conc. (g/mL) | pH |
| 1.0052 | yes | 0.101 | 4.32 |
| 1.5045 | yes | 0.150 | 4.01 |
| 2.0013 | yes | 0.200 | 4.11 |
| 2.4954 | yes | 0.250 | 4.04 |
| 3.0074 | yes | 0.301 | 4.17 |
| 3.5021 | yes | 0.350 | 3.93 |
| 4.0012 | yes | 0.400 | 3.88 |
| 4.4986 | yes | 0.450 | 3.87 |
| 5.0134 | yes | 0.501 | 3.79 |
| 5.5113 | yes | 0.551 | 3.75 |
| 6.0009 | yes | 0.600 | 3.72 |
| 6.5091 | yes | 0.651 | 3.69 |
| 6.9808 | yes | 0.698 | 3.67 |
| 7.5156 | yes | 0.752 | 3.62 |
| 8.0053 | yes | 0.801 | 3.60 |
| 8.4894 | yes | 0.849 | 3.56 |
| 9.0072 | yes | 0.901 | 3.56 |
| 9.4949 | yes | 0.949 | 3.56 |
| 10.0043 | no | 10.000 | not applicable |
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The water solubility of the substance at 25 °C was estimated to be 0.95 g/cm3 < water solubility < 1.00 g/cm3 by visual observation (in accordance with EC A.6 and OECD 105 guidelines). The pH range of the water fraction after the test was between 3.56 and 4.32.
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