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EC number: 602-997-3 | CAS number: 124495-18-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- column elution method
- Specific details on test material used for the study:
- Substance ID: TSN104816
Lot number: F50-E1662-51
Purity: 99.8% - Key result
- Water solubility:
- 0.12 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- Remarks on result:
- other: Purified water
- Key result
- Water solubility:
- 0.12 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 5
- Key result
- Water solubility:
- 0.11 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 7
- Key result
- Water solubility:
- 0.11 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 9
- Conclusions:
- Solubilities determined at 20°C:
Purified water: 0.12 mg/L
pH 5 buffer solution: 0.12 mg/L
pH 7 buffer solution: 0.11 mg/L
pH 9 buffer solution: 0.11 mg/L - Executive summary:
The solubility of the test substance was determined in purified water and buffer solutions at pH 5, 7 and 9 following the guidelines OECD Guideline 105, EU Method A.6 and EPA OPPTS 830.7840. Preliminary tests to measure the solubility were performed by stirring known masses of test substance with known volumes of either purified water, pH 5, 7 or 9 buffer solutions for 96 hours. At this stage, further preliminary work was conducted in which samples from the tests were analysed by a chromatography method. The solubility was subsequently determined by the column elution method.
The following solubilities were determined for the test substance at 20°C:
Purified water: 0.12 mg/L
pH 5 buffer solution: 0.12 mg/L
pH 7 buffer solution: 0.11 mg/L
pH 9 buffer solution: 0.11 mg/L
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: EPA/FIFRA subdivision D 63-8
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: flask shake method
- Specific details on test material used for the study:
- Substance ID: TSN 100004
Name of substance: XDE-795 (pure)
Purity: 99.7% - Key result
- Water solubility:
- 116 µg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- Remarks on result:
- other: distilled water
- Key result
- Water solubility:
- 128 µg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 5
- Key result
- Water solubility:
- 47 µg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 7
- Key result
- Water solubility:
- 36 µg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 9
- Conclusions:
- Solubilities determined at 20°C:
Distilled water: 116 µg/L
pH 5 buffer solution: 128 µg/L
pH 7 buffer solution: 47 µg/L
pH 9 buffer solution: 36 µg/L - Executive summary:
The solubility of the test substance was determined in purified water and buffer solutions at pH 5, 7 and 9 following the guidelines OECD Guideline 105 and EU Method A.6. A preliminary test to measure the solubility of the test substance, by shaking a weighed amount with increasing volumes of ultra-high purity water. The solubilities of the test substance in buffer solutions at pH 5.0, pH 7.0 and pH 9.0 were determined by the flask shake method.
The following solubilities were determined for the test substance at 20°C:
Distilled water: 116 µg/L
pH 5 buffer solution: 128 µg/L
pH 7 buffer solution: 47 µg/L
pH 9 buffer solution: 36 µg/L
Referenceopen allclose all
Description of key information
OECD guideline 105; EU Method A.6; OPPTS 830.7840
Key value for chemical safety assessment
- Water solubility:
- 0.11 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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