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EC number: 500-058-1 | CAS number: 27252-75-1 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 31 Jan - 28 Feb 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 1992
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Sewage treatment micro-organisms from the final effluent stage of the Severn Trent Water Plc sewage treatment plant at Loughborough, Leicestershire, UK (obtianed on 28 Jan 2019). The STP treats predominantly domestic sewage.
- Pretreatment: The sample of effluent was filtered through coarse filter paper (first approximate 200 mL discarded) and maintained on aeration in a temperature controlled room at temperatures of between 20 and 21 °C prior to use. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to OECD guideline
- Solubilising agent (type and concentration if used): the test item was dissolved directly in mineral medium with the aid of ultrasonication for appr. 20 minutes.
- Test temperature: 21 - 22 °C
- pH: 7.4-7.5
- pH adjusted: no
- Continuous darkness: no (diffuse light)
TEST SYSTEM
- Culturing apparatus: CES Multi-Channel Aerobic Respirometer
- Number of culture flasks/concentration: 3
- Method used to create aerobic conditions: the pressure reduction caused by the adsobtion of carbon dioxide triggers an electrolytic process, generating oxygen and restoring the pressure in the sample flask.
- Details of trap for CO2 and volatile organics if used: ethanolamine solution (50% v/v)
CONTROL AND BLANK SYSTEM
- Inoculum blank: 3 replicates
- Reference item control: 2 replicates
- Toxicity control: 2 replicates (100 mg test item/L and 100 mg aniline/L) - Reference substance:
- aniline
- Parameter:
- % degradation (O2 consumption)
- Value:
- 100
- Sampling time:
- 28 d
- Details on results:
- Degradation rate of toxicity control: 76% after 14 days. The test substance is not toxic to micro-organisms.
- Results with reference substance:
- Reference contol (Anilin): 76% degradation after 14 days (ten-day window criterion met)
- Validity criteria fulfilled:
- yes
- Remarks:
- For further details please refer to table 2 in “Any other information on results incl. tables”.
- Interpretation of results:
- readily biodegradable
Reference
Table 1: Percentage Biodegradation Values
Day |
Biodegradation (%) |
||||
Procedure Control |
Test Item |
Toxicity Control |
|||
R1 |
R2 |
Mean |
|||
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
1 |
0 |
1 |
0 |
2 |
0 |
23 |
23 |
23 |
10 |
3 |
0 |
29 |
29 |
29 |
12 |
4 |
3 |
39 |
39 |
39 |
17 |
5 |
21 |
54 |
53 |
54 |
28 |
6 |
39 |
63 |
63 |
63 |
39 |
7 |
59 |
69 |
70 |
70 |
49 |
8 |
64 |
73 |
74 |
74 |
62 |
9 |
66 |
77 |
77 |
77 |
71 |
10 |
67 |
80 |
81 |
81 |
73 |
11 |
69 |
82 |
86 |
84 |
74 |
12 |
70 |
84 |
89 |
87 |
75 |
13 |
70 |
88 |
91 |
90 |
76 |
14 |
71 |
90 |
93 |
92 |
76 |
15 |
71 |
91 |
94 |
93 |
77 |
16 |
72 |
92 |
95 |
94 |
78 |
17 |
72 |
93 |
96 |
95 |
78 |
18 |
72 |
94 |
97 |
96 |
78 |
19 |
73 |
94 |
98 |
96 |
79 |
20 |
73 |
95 |
98 |
97 |
79 |
21 |
73 |
95 |
99 |
97 |
80 |
22 |
74 |
96 |
99 |
98 |
80 |
23 |
74 |
96 |
100 |
98 |
80 |
24 |
74 |
97 |
100 |
99 |
80 |
25 |
74 |
97 |
100 |
99 |
80 |
26 |
75 |
97 |
100 |
99 |
80 |
27 |
75 |
97 |
101 |
99 |
80 |
28 |
75 |
98 |
101 |
100 |
80 |
R= Replicate
Table 2: Validity criteria for OECD 301.
Criterion from the guideline |
Outcome |
Validity criterion fulfilled |
Difference of extremes of replicate values of the removal of the test chemical at the plateau, at the end of the test or at the end of the 10-d window, as appropriate, is less than 20%. |
<20% |
yes |
Percentage degradation of the reference compound reached the pass level by day 14 (≥ 60%). |
71% after 14 days |
yes |
The toxicity control should degrade to at least 35% (based on DOC) or at least 25% (based on ThOD or ThCO2) within 14 d. |
76% after 14 days |
yes |
The oxygen uptake of the inoculum blank is normally 20-30 mg O2/L and should not be greater than 60 mg/L in 28 days. |
39.60 mg O2/L |
yes |
Description of key information
Readily biodegradable: 100% after 28 days (OECD 301F)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The ready biodegradability of Octan-1-ol, ethoxylated, < 2.5 EO was assessed in a study following OECD guideline 301 F. The O2 consumption of non-adapted activated sludge at a test material concentration of 100 mg/L was followed for 28 days. A degradation rate of 100% was reached after 28 days and the ten-day window criterion was met.
The substance is assessed as readily biodegradable according to OECD criteria.
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