Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Toxicity to reproduction

Currently viewing:

Administrative data

Endpoint:
reproductive toxicity, other
Remarks:
.
Type of information:
other: assessment
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: assessment
Justification for type of information:
Justification of Read Across is given in Section 13 of IUCLID

Data source

Reference
Reference Type:
other: Assessment
Title:
Unnamed
Year:
2020

Materials and methods

Principles of method if other than guideline:
Assessment
GLP compliance:
no
Remarks:
Assessment

Test material

Constituent 1
Chemical structure
Reference substance name:
Hexadecan-1-ol
EC Number:
253-149-0
EC Name:
Hexadecan-1-ol
Cas Number:
36653-82-4
Molecular formula:
C16H34O
IUPAC Name:
1-Hexadecanol

Test animals

Species:
rat

Results and discussion

Results: P0 (first parental generation)

Effect levels (P0)

Dose descriptor:
NOAEL
Remarks on result:
other: Assessment

Target system / organ toxicity (P0)

Critical effects observed:
not specified

Results: P1 (second parental generation)

Effect levels (P1)

Dose descriptor:
NOAEL
Remarks on result:
other: Assessment

Target system / organ toxicity (P1)

Critical effects observed:
not specified

Results: F1 generation

Effect levels (F1)

Dose descriptor:
NOAEL
Remarks on result:
other: Assessment

Target system / organ toxicity (F1)

Critical effects observed:
not specified

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion