Registration Dossier
Registration Dossier
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EC number: 953-917-1 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- A discussion and report on the read across strategy is given as an attachment in IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: non-inhibitory
- Details on results:
- HF-1000 attained 43% degradation after 28 day, while the toxicity control attained 45% degradation after 14 days and 58% degradation after 28 days. The results of the toxicity control confirm that HF-1000 was not toxic to the sewage treatment micro-organisms used in the test.
- Results with reference substance (positive control):
- Aniline attained 69% degradation after 14 days and 73% degradation after 28 days confirming the viability of the inoculum and suitability of the test conditions.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The toxicity control in the OECD 301F study which contained 100 mg/L Hydrocarbons, C12-C16, n-alkanes, isoalkanes, alkenes and 100 mg/L of anline attained 45% degradation after 14 days and 58% degradation after 28 days. These results of the toxicity control confirm that Hydrocarbons, C12-C16, n-alkanes, isoalkanes, alkenes was not toxic to the sewage treatment micro-organisms used in the test.
- Executive summary:
In an OECD 301F study, the toxicity control which contained 100 mg/L Hydrocarbons, C12-C16, n-alkanes, isoalkanes, alkenes and 100 mg/L of aniline confirmed that Hydrocarbons, C12-C16, n-alkanes, isoalkanes, alkenes was not toxic to the sewage treatment micro-organisms used in the test.
Reference
Description of key information
The study was conducted according to a standard guideline (OECD 301F) under GLP
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
In an OECD 301F study, the toxicity control which contained 100 mg/L Hydrocarbons, C12-C16, n-alkanes, isoalkanes, alkenes and 100 mg/L of aniline confirmed that Hydrocarbons, C12-C16, n-alkanes, isoalkanes, alkenes was not toxic to the sewage treatment micro-organisms used in the test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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