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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 JUL 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- effusion method: Knudsen cell
- Temp.:
- 20 °C
- Vapour pressure:
- >= 0 - <= 0 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- >= 0 - <= 0 Pa
- Conclusions:
- Vapour pressure of test item at 20 °C: >= 7.5E-7 Pa - <= 1.02E-6 Pa
Vapour pressure of test item at 25 °C: >= 1.35E-6 Pa - <= 1.83E-6 Pa - Executive summary:
Vapour pressure of the test item was determined using Vapor Pressure Analyzer (Knudsen Effusion Method) following internationally accepted guidelines (OECD 104, EU Method A.4) in a non-GLP study.
The vapour pressure was measured in the temperature range of 30 to 150 °C. For the evaluation the vapour pressure values in the range of 105 to 135 °C were used.
The following results were obtained:
Vapour pressure of test item at 20 °C: >= 7.5 x 10 -7 Pa - <= 1.02 x 10 -6 Pa
Vapour pressure of test item at 25 °C: >= 1.35 x 10 -6 Pa - <= 1.83 x 10 -6 Pa
The molecular weight range is for the whole substance, therefore the whole substance has a range for the vapour pressure.
Reference
Observations
105°C.At the first measurement of experiment 6, the pump of the test system was defected. To avoid bias, this measurement was not used for calculations. This measured weight was used as initial weight for the subsequent measurements.
105°C.At the second measurement of experiment 6, all cells were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
105°C.At the third measurement of experiment 6, cell 2 and 4 were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
105°C.At the fourth measurement of experiment 6, cell 3 was slightly contaminated. Therefore, the cell was meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
120°C.At the first measurement of experiment 7, cell 4 was slightly contaminated. Therefore, the cell was meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
120°C.At the second measurement of experiment 7, all cells were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
135°C.At the second measurement of experiment 8, all cells were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
135°C.At the third measurement of experiment 8, cell 2 and 4 were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
Results for the molecular mass of 457 g/mol
The measured values for temperature and vapour pressure were evaluated as follows:
Parameter | T [°C] | T [K] | p [Pa] | 1/T [1/K] | log p [log Pa] |
Values |
105.0 |
378.2 |
2.55 x 10-3 |
2.6441 x 10-3 |
-2.5937 |
120.0 |
393.2 |
8.63 x 10-3 |
2.5432 x 10-3 |
-2.0642 |
|
135.0 |
408.2 |
1.87 x 10-2 |
2.4498 x 10-3 |
-1.7282 |
A graph with log p vs. 1/T was plotted. Since the values were correlated by a linear relation, the data could be fitted by linear regression. y = -4464.6 x + 9.237 with r2= 0.9887.
For the test substance, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
Vapour pressure at 20 °C: 1.02 x 10 -06 Pa
Vapour pressure at 25 °C: 1.83 x 10 -06 Pa
Results for the molecular mass of 840 g/mol
The measured values for temperature and vapour pressure were evaluated as follows:
Parameter | T [°C] | T [K] | p [Pa] | 1/T [1/K] | log p [log Pa] |
Values |
105.0 |
378.2 |
1.88 x 10-03 |
2.6441 x 10-3 |
-2.7259 |
120.0 |
393.2 |
6.36 x 10-3 |
2.5432 x 10-3 |
-2.1964 |
|
135.0 |
408.2 |
1.38 x 10-2 |
2.4498 x 10-3 |
-1.8603 |
A graph with log p vs. 1/T was plotted. Since the values were correlated by a linear relation, the data could be fitted by linear regression. y = -4464.6 x + 9.1048 with r2= 0.9887.
For the test substance, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
Vapour pressure at 20 °C: 7.50 * 10 -07 Pa
Vapour pressure at 25 °C: 1.35 * 10 -06 Pa
The molecular weight range is for the whole substance, therefore the whole substance has a range for the vapour pressure.
Description of key information
Vapour pressure of the test item was determined using Vapor Pressure Analyzer (Knudsen Effusion Method) following internationally accepted guidelines (OECD 104, EU Method A.4).
The vapour pressure was measured in the temperature range of 30 to 150 °C. For the evaluation the vapour pressure values in the range of 105 to 135 °C were used.
The following results were obtained:
Vapour pressure of test item at 20 °C: >= 7.5 x 10-7 Pa - <= 1.02 x 10-6 Pa
Vapour pressure of test item at 25 °C: >= 1.35 x 10 -6 Pa - <= 1.83 x 10 -6 Pa
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
The substance has based on its composition different constituents and therefore a range in the molecular weight. The vapour pressure is calculated for the upper and lower limit of the range. The value indicated as key value for the chemical safety assessment is the highest determined vapour pressure for the substance and regarded as worst-case scenario.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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