Registration Dossier
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EC number: 224-226-6 | CAS number: 4253-90-1
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
A fish bioaccumulation study was carried out (2015) on Bluegill sunfish according to OECD TG 305 (rev. 2012), through dietary exposure. A BMFkgL of 0.0059 was obtained, from which a BCFkgL = 188 is calculated
Key value for chemical safety assessment
- BCF (aquatic species):
- 188 dimensionless
Additional information
Polysulfide di-tert-butyl bioaccumulation potential was determined through dietary exposure of freshwater fish Bluegill sunfish (Lepomis macrochirus) according to the OECD TG 305 (rev. 2012). The test item was the commercial substance TPS 44. In parallel, the approriateness of the test design was checked by exposing a lot of fish to HCB (hexachlorobenzene) as a positive control.
The BMF obtained for the TPS 44 was corrected for fish growth an lipid content, as recommened by the guideline, resulting in a BMFkgL = 0.0059.
There is not a unique way for converting BMF to BCF in order to compare with regulatory threshold for the "B" or "vB" criterion. Two methods were assayed, the allometric method described by Sijm et al (1995), which proved to be unsuitable it the present case due to poor assimilation efficiency, and the empirical method of Inoue et al. (2011) through which a BCFkgL = 188 can be calculated (through Inoue's equation, a BCF of 2000 corresponds approximately to a BMF of 0.1 and a BCF of 5000 to a BMF of 0.31).
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