3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol

Adsorption / desorption

Administrative data

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Data source

Reference

Reference Type:

publication

Title:

Unnamed

Year:

2007

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)

Deviations:

yes

Remarks:

3 soils used

GLP compliance:

not specified

Type of method:

batch equilibrium method

Media:

soil

Test material

Test material information

Constituent 1

Reference substance name:

3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol

EC Number:

211-477-1

EC Name:

3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol

Cas Number:

647-42-7

Molecular formula:

C8H5F13O

IUPAC Name:

3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol

Test material form:

other: liquid

Details on test material:

- Purity: ≥ 97%

Radiolabelling:

no

Study design

Test temperature:

22.5 ± 0.4ºC

Batch equilibrium or other method

Analytical monitoring:

no

Details on matrix:

COLLECTION AND STORAGE
- Soil preparation: To sterilise soils and inhibit microbial activity in the aqueous sorption studies, 60Co(γ)-irradiation was used prior to addition of the test compounds. Air-dried (<2 mm) soils were incubated moist for 1-2 days at room temperature, irradiated, and the whole process was repeated 3 times for a cumulative dosage of 3.2 Mrad.


PROPERTIES
- soil 7CB2 is a silt loam with 8.18% organic carbon (OC) and pH of 5.30
- soil Drummer-6 is a clay loam with 2.50% OC and pH of 5.80
- soil Oakville-24 is a sandy loam with 0.52% OC and pH of 4.40

Details on test conditions:

TEST CONDITIONS
- Suspended solids concentration: Soil to solution ratios (g:mL) were selected to target 20-80% sorption of applied mass with ratios of 1:2 to 1:5.



TEST SYSTEM
- Type, size and further details on reaction vessel: 8-mL glass tubes with aluminum-lined septum caps,
- Water filtered: deionised water (g17.8Mcm) came from a Barnstead E-pure system, water and lab ware used for aqueous measurements were autoclaved to reduce biotransformation potential
- Number of reaction vessels/concentration: 2
- Test performed in closed vessels due to significant volatility of test substance: yes
- Method of preparation of test solution: The test substance was added directly to soils in a methanol stock solution using a microsyringe giving six initial concentrations of 0.30-3.00 mg/L.

Duration of adsorption equilibration

Duration:

2 d

Temp.:

22.5 °C

Computational methods:

Statistical Analysis System (SAS) Software was used to fit the isotherm data to the Freundlich sorption model, Cs = Kf CwN, where Cw (mg/L) and Cs (mg/kg) are the solution and sorbed phase concentrations at equilibrium, Kf is the Freundlich sorption coefficient (mg1-N LN /kg) and N (unitless) is a measure of isotherm nonlinearity, as well as the linear sorption model: Cs = KdCw where Kd (L/kg) is the linear sorption coefficient.

Results and discussion

Adsorption coefficient

Type:

log Koc

Value:

2.43

Temp.:

22.5 °C

% Org. carbon:

>= 0.52 - <= 8.18

Results: Batch equilibrium or other method

Recovery of test material:

- soil 7CB2: Isotherm 1 - 56.2%, Isotherm 2 - 86.1%
- soil Drummer-6: Isotherm 1 - 51.8%, Isotherm 2 - 66.9%
- soil Oakville-24: Isotherm 1 - 105.0%, Isotherm 2 - Not Determined

Transformation products:

not specified

Details on results (Batch equilibrium method):

MAIN TEST: PERFORMANCE
- Initial test substance concentration: six initial concentrations of 0.30-3.00 mg/L.
- Test material stability during adsorption phase: Yes
- Experimental conditions maintained throughout the study: Yes:
- Anomalies or problems encountered (if yes): Several possible causes of low recovery such as photolysis, volatility, irreversible sorption, and biotransformation were considered, but biotransformation was determined to be the predominant source of low mass recoveries.

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

This study and the conclusions which are drawn from it fulfil the quality criteria (validity, reliability, repeatability).

log Koc = 2.43

Executive summary:

Three soils with Organic Carbon content of 0.52 to 8.18% were used to determine the log Koc of the test substance. Six concentrations ( 0.30 - 3.00 mg/L) were prepared in duplicate, equilibrated for 2 days, centrifuged, extracted and analysed by LC/MS/MS. Data were subject to the Freundlich sorption model and the log Koc determined to be 2.43.