Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

(S)-1-(3-Methoxyphenyl)ethylamine (read across, CAS 82796-69-8) was tested for its sensitizing effect on the skin of the guinea pig in the Maximization Test based on the method of Magnusson and Kligman. The study was performed using one control group and one test group. Based on the results it was concluded, that (S)-1-(3-Methoxyphenyl)ethylamine showed a strong sensitizing potential. [BASF, 2008]

Migrated from Short description of key information:
The results of this study show that (S)-1-(3-Methoxyphenyl)ethylamine (read across, CAS 82796-69-8) had a sensitizing effect on the skin of the guinea pig in the Maximization Test (OECD 406) under the test conditions.

Justification for classification or non-classification

Based on the available data for (S)-1-(3-Methoxyphenyl)ethylamine (read across, CAS 82796-69-8) rac-1-(4-Methylphenyl)ethylamine

is subject to C&L:

according to Regulation 1272/2008/EC: sensitizing cat. 1A, H317

according to Directive 67/548/EEC: sensitizing: R43